Evidence map›Paper›PMID 32123737›Full record

ArticleACS central science2020

Characterization of Autoinducer-3 Structure and Biosynthesis in

Chung Sub Kim, Alexandra Gatsios, Santiago Cuesta, Yick Chong Lam, Zheng Wei, Haiwei Chen, Regan M Russell, Emilee E Shine, Rurun Wang, Thomas P Wyche and 5 more

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
15.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 136 citations in OpenAlex.

  1. The Tryptophan Biosynthesis GeneAnimals : an open access journal from MDPI · 2026
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  13. Cooperativity inInternational journal of molecular sciences · 2025
    Article
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  16. Article
  17. Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Chung Sub KimDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Alexandra GatsiosDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Santiago CuestaDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Yick Chong LamDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Zheng WeiChemical Biology Institute, Yale University, West Haven, Connecticut 06516, United States.
Haiwei ChenDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, United States.
Regan M RussellDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Emilee E ShineChemical Biology Institute, Yale University, West Haven, Connecticut 06516, United States.
Rurun WangMerck Exploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts 02141, United States.
Thomas P WycheMerck Exploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts 02141, United States.
Grazia PiizziMerck Exploratory Science Center, Merck & Co., Inc., Cambridge, Massachusetts 02141, United States.
Richard A FlavellDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, United States.
Noah W PalmDepartment of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, United States.
Vanessa SperandioDepartment of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
Jason M CrawfordDepartment of Chemistry, Yale University, New Haven, Connecticut 06520, United States.
Yale University · USMerck & Co., Inc., Rahway, NJ, USA (United States) · USThe University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · US

Funding

Quorum sensing regulation of EHEC virulence genesR01AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SPERANDIO, VANESSA · 2003 to 2017
$6.3M
Structural and functional studies of colibactinR01CA215553 · NCI · YALE UNIVERSITY · PI Seth B. Herzon, Christian Jobin · 2018 to 2026
$5.5M
Quorum Sensing Regulation of EHEC Virulence GenesR37AI053067 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VANESSA SPERANDIO · 2018 to 2026
$5.3M
Cryptic gut bacterial metabolites that regulate colorectal cancer formationDP2CA186575 · NCI · YALE UNIVERSITY · PI CRAWFORD, JASON MICHAEL · 2013 to 2013
$2.5M
EPA EP-W-17-011NCI NIH HHS DP2 CA186575NCI NIH HHS R01 CA215553NIAID NIH HHS R01 AI053067NIAID NIH HHS R37 AI053067
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32123737
PMCPMC7047286
OpenAlexW3002508406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.