Evidence map›Paper›PMID 32123733›Full record

ArticleACS central science2020

Sensing Living Bacteria

Matthew F L Parker, Justin M Luu, Brailee Schulte, Tony L Huynh, Megan N Stewart, Renuka Sriram, Michelle A Yu, Salma Jivan, Peter J Turnbaugh, Robert R Flavell and 3 more

Open access · diamondAbstract read
In one paragraph

Article in ACS central science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Automated radiosynthesis of [EJNMMI radiopharmacy and chemistry · 2025
    Article
  10. d-[5-ACS infectious diseases · 2025
    Article
  11. Article
  12. Evaluation of [Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  13. Biological Evaluation of d-[Journal of medicinal chemistry · 2024
    Article
  14. Pilot Evaluation of S-(3-[Molecular imaging and biology · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. In Vivo Detection ofInternational journal of biomedical imaging · 2024
    Article
  20. The Development and Validation of Radiopharmaceuticals Targeting Bacterial Infection.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Matthew F L ParkerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Justin M LuuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Brailee SchulteDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Tony L HuynhDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Megan N StewartDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Renuka SriramDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Michelle A YuDepartment of Medicine, University of California, San Francisco, San Francisco, California 94158, United States.
Salma JivanDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Peter J TurnbaughDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California 94158, United States.
Robert R FlavellDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
Oren S RosenbergDepartment of Medicine, University of California, San Francisco, San Francisco, California 94158, United States.
Michael A OhligerDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
David M WilsonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, California 94158, United States.
University of California, San Francisco · USSan Francisco General Hospital · US

Funding

Development of 11C-PABA as a bacteria-specific imaging agent for spinal infectionsR01EB025985 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAIN, SANJAY, WILSON, DAVID M · 2018 to 2021
$2.7M
Clinical translation of D-amino acid derived PET tracers for imaging spinalinfectionR01EB024014 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OHLIGER, MICHAEL, WILSON, DAVID M · 2017 to 2020
$2.2M
Development of methodologies and probes for metabolic detection of pathogenic microorganismsR03AI138189 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SRIRAM, RENUKA · 2018 to 2019
$160k
NIAID NIH HHS R03 AI138189NIBIB NIH HHS R01 EB024014NIBIB NIH HHS R01 EB025985
6 · The paper itself

Abstract

Incorporation of d-amino acids into peptidoglycan is a unique metabolic feature of bacteria. Since d-amino acids are not metabolic substrates in most mammalian tissues, this difference can be exploited to detect living bacteria

Identifiers

PMID32123733
PMCPMC7047270
OpenAlexW3004553650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.