ArticleJournal of advanced research2020
The effect of increased femoral anteversion on the morphological and trabecular microarchitectural changes in the trochlea in an immature rabbit.
Article in Journal of advanced research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Cartilage degeneration is associated with activation of the PI3K/AKT signaling pathway in a growing rat experimental model of developmental trochlear dysplasia.Journal of advanced research · 2022Trial
- Differences between skeletally immature and mature patients in recurrent patellar dislocation: a radiological study.Journal of orthopaedic surgery and research · 2026Article
- Abnormal mechanical stress due to excessive femoral torsion is associated with dysplasia of the distal femoral epiphyseal plate and trochlea.Bone & joint research · 2025Article
- Hindlimb Suspension and Subsequent Weight-Loading on Femoral Morphology, Knee Joint Alignment, and Patellar Tracking in Growing Rats.Journal of musculoskeletal & neuronal interactions · 2025Article
- Multi-Omics insights into the molecular mechanisms of trochlear dysplasia: A proteomic and metabolomic study in rats.PloS one · 2025Article
- Distal femoral torsion is correlated with higher-grade trochlear dysplasia and shorter anterior condyles in patients with patellar dislocation and increased femoral torsion.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Patellar instability-induced bone loss in the femoral trochlea is associated with the activation of the JAK1/STAT3 signaling pathway in growing mice.Journal of orthopaedic surgery and research · 2023Article
- Comparison of Habitual Versus Recurrent Patellar Dislocation in Children and Adolescents: Differences in Radiological Features.Orthopaedic journal of sports medicine · 2023Article
- Patellofemoral joint load and knee abduction/adduction moment are sensitive to variations in femoral version and individual muscle forces.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Pathological Thresholds of Segmental Femoral Torsion in Patients With Patellar Dislocation: Influence on Patellofemoral Malalignment.Orthopaedic journal of sports medicine · 2022Article
- RNA-seq based integrative analysis of potential crucial genes and pathways associated with patellar instability.Bioengineered · 2022Article
- Increased femoral antetorsion correlates with higher degrees of lateral retropatellar cartilage degeneration, further accentuated in genu valgum.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased femoral anteversion (FA) has been recently demonstrated as one risk factor for recurrent patellar dislocation (RPD). However, it has been still unclear whether the increase of FA can result in patellar dislocation, and subsequent morphological and trabecular microarchitectural changes in the trochlea has not been investigated. Forty knees from 20 rabbits at 3 months of age were included. The right knees underwent surgery with internal rotation of distal femur to increase FA, with the left knees acting as internal controls. The surgical knees were called operated group, and non-operated knees were control group. Micro-CT scans for distal femur were acquired after 4 months of surgery. In the operated group, a boss located proximal to the entrance of the groove was formed. The central trochlear height was significantly greater, sulcus angle was significantly greater, both lateral and medial trochlear slope were significantly lower, and boss height was significantly greater in comparison to the control group. Regarding the microarchitectural changes, the trabecular thickness were increased by 67.5% at the groove, 33.0% and 29.5%, at the medial and lateral femoral condyle, and trabecular number were decreased by 37.8% and 26.5% at the groove and medial femoral condyle. This study provided a novel animal model of trochlea dysplasia by femoral rotational osteotomy and increased FA. These changes were associated with the load redistribution in the patellofemoral joint after the increase of FA.
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