ReviewThe Japanese dental science review2020
Oral management strategies for radiotherapy of head and neck cancer.
Review in The Japanese dental science review, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it, 114 citations in OpenAlex.
- Pooled it
- Prevention of pain and oral mucositis in patients undergoing chemotherapy through the use of a high-energy light source: A randomized clinical study.Lasers in medical science · 2025Trial
- Trial
- A randomised controlled trial of clinical pharmacy intervention versus standard care to improve medication adherence in outpatients with head and neck cancer receiving radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Trial
- Reporting quality and spin in abstracts of randomized clinical trials related to oral mucositis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Hospitalized Patients with Oral Cavity Cancer and Ulcerative Mucositis: Implications for Key Cost Drivers and Disparities.Reports (MDPI) · 2026Article
- Educational Interventions in Oral Hygiene for Patients Undergoing Head and Neck Cancer Radiotherapy: A Feasibility Study.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- Dose-Dependent Effects of Simulated Clinical Radiotherapy on the Structure and Properties of Root Dentine.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Network analysis of symptom clusters and core symptom changes in nasopharyngeal cancer survivors: a longitudinal study.Journal of cancer survivorship : research and practice · 2026Article
- Surface-engineered hydrophobic hydrogels via cholesterol micelle rearrangement for robust wet adhesion and oral mucositis therapy.Materials today. Bio · 2025Article
- The synergistic potential of ultrasound and nanomaterials for enhanced diagnosis and therapy of head and neck cancers.Nanomedicine (London, England) · 2025Review
- Role of diode laser (810 nm) and/or fluoride varnish for the treatment of gamma-irradiated hypersensitive human dentin (An in vitro study).Scientific reports · 2025Article
- Prevention of osteoradionecrosis in patients with head and neck cancer treated with radiation therapy.Head & neck · 2025Article
- Radiotherapy-Associated Oral Lesions in a Geriatric Patient with Nasal Squamous Cell Carcinoma: A Case Report.International medical case reports journal · 2025Article
- Article
- Review
- Correlation Analysis Between Prognostic Nutritional Index Trajectory Categories and Radiotherapy-induced Severe Oral Mucositis in Head and Neck Cancer Patients Undergoing Radiotherapy.Oral health & preventive dentistry · 2024Observational
- The Effectiveness of Curcumin in Treating Oral Mucositis Related to Radiation and Chemotherapy: A Systematic Review.Antioxidants (Basel, Switzerland) · 2024Review
- The Association of Salivary Flow Rate and Sleep Quality among Head and Neck Cancer Survivors after Radiotherapy.BMC oral health · 2024Article
- Evaluation of positioning accuracy in head-and-neck cancer treatment: A cone beam computed tomography assessment of three immobilization devices with volumetric modulated arc therapy.Journal of biological methods · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiotherapy, often with concomitant chemotherapy, has a significant role in the management of head and neck cancer, however, radiotherapy induces adverse events include oral mucositis, hyposalivation, loss of taste, dental caries, osteoradionecrosis, and trismus, all of which have an impact on patients' quality of life. Therefore, it is necessary to implement oral management strategies prior to the initiation of radiotherapy in patients with head and neck cancer. Since 2014, the National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology (NCCN Guidelines) have enumerated the "Principles of Dental Evaluation and Management (DENT-A)" in the section on head and neck cancers, however, oral management was not explained in detail. Oral management has not been achieved a consensus protocol. The aim of this literature is to show that oral management strategy include removal infected teeth before the start of radiotherapy to prevent osteoradionecrosis, oral care for preventing severe oral mucositis to support patient complete radiotherapy during radiotherapy, and prevent of dental caries followed by osteoradionecrosis after radiotherapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.