ArticleNature biotechnology2020
MEMOTE for standardized genome-scale metabolic model testing.
Erratum issuedAbstract readLetter
In one paragraph
Article in Nature biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 293 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
293citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
293 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Leveraging genome-scale metabolic models to understand aerobic methanotrophs.The ISME journal · 2024Pooled it
- Pan-Genome-Scale Metabolic Reconstruction Reveals Conserved Metabolic Functions inJournal of fungi (Basel, Switzerland) · 2026Article
- BioEMMA: Automated Generation of Model-Specific Escher-Compatible Maps from KEGG Pathways.Biology · 2026Article
- A metabolic model of the leaf-associated bacteriummSystems · 2026Article
- Environmental formermSystems · 2026Article
- AlphaGEM enables precise genome-scale metabolic modelling by integrating protein structure alignment with deep-learning-based dark metabolism mining.Nature communications · 2026Article
- Integrated multi-dimensional modeling of non-model bacteria identifies engineering targets for acarbose biosynthesis optimization.Cell reports methods · 2026Article
- Nutrient control enables metabolic reconstruction ofbioRxiv : the preprint server for biology · 2026Article
- Transcriptome-constrained genome-scale metabolic modeling reveals central carbon and amino acid metabolic reprogramming underlying colistin-sulbactam synergy inAntimicrobial agents and chemotherapy · 2026Article
- High-Quality Genome Assembly, Metabolome, Pangenome, and Metabolic Models of Megasphaera hexanoica KCCM 43214Scientific data · 2026Article
- Genome-Scale Metabolic Models Guided Improvement of Fermented Milk Quality and Flavor byFoods (Basel, Switzerland) · 2026Article
- Selecting methods for draft GEM generation in multicellular eukaryotes: a comparative analysis.BMC bioinformatics · 2026Article
- Incorporation of Cryptic Plasmid Energetics Improves Genome-Scale Metabolic Predictions in Probiotic E. coli Nissle 1917.Microbial biotechnology · 2026Article
- Multi-strain analysis ofmSystems · 2026Article
- Reconstruction of human metabolic models with large language models.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- EHMN 2026: A Thermodynamically Refined, SBML-Standardised Human Metabolic Network for Genome-Scale Analysis and QSP Integration.Metabolites · 2026Article
- From FAIR to CURE: guidelines for computational models of biological systems.NPJ systems biology and applications · 2026Review
- Enzyme-constrained genome-scale model of Yarrowia lipolytica predicts growth-phase specific metabolic engineering targets.Applied microbiology and biotechnology · 2026Article
- Investigating the impact of carbamazepine on tomato plant metabolism using genome-scale metabolic modelling.Scientific reports · 2026Article
- An ecology-driven microbial consortium enhances plant growth and immunity while sustaining rhizospheric microbial balance.Plant communications · 2026Article
233 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
69 authors.
Christian Lieven *Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0001-5377-4091
Moritz E Beber *Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0003-2406-1978
Brett G OlivierSystems Biology Lab, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-5293-5321
Frank T BergmannBioQUANT/COS, Heidelberg University, Heidelberg, Germany.
Meric AtamanEcole Polytechnique Fédérale de Lausanne, Laboratory of Computational Systems Biotechnology, Lausanne, Switzerland.
Parizad BabaeiNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Jennifer A BartellNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0003-2750-9678
Lars M BlankiAMB-Institute of Applied Microbiology, ABBt-Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.
Siddharth ChauhanDepartment of Bioengineering, University of California, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6674-895X
Kevin CorreiaDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0001-7130-1765
Christian DienerHuman Systems Biology Laboratory, Instituto Nacional de Medicina Genomica & Coordinación de la Investigación Científica-Red de Apoyo a la Investigación, UNAM, Mexico City, Mexico.
Andreas DrägerComputational Systems Biology of Infection and Antimicrobial-Resistant Pathogens, Institute for Biomedical Informatics (IBMI), Tübingen, Germany.ORCID http://orcid.org/0000-0002-1240-5553
Birgitta E EbertiAMB-Institute of Applied Microbiology, ABBt-Aachen Biology and Biotechnology, RWTH Aachen University, Aachen, Germany.
Janaka N EdirisingheArgonne National Laboratory, Lemont, IL, USA.
José P FariaArgonne National Laboratory, Lemont, IL, USA.
Adam M FeistNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0002-8630-4800
Georgios FengosEcole Polytechnique Fédérale de Lausanne, Laboratory of Computational Systems Biotechnology, Lausanne, Switzerland.
Ronan M T FlemingAnalytical Biosciences, Division of Systems Biomedicine and Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.ORCID http://orcid.org/0000-0001-5346-9812
Beatriz García-JiménezDepartment of Systems Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.
Vassily HatzimanikatisEcole Polytechnique Fédérale de Lausanne, Laboratory of Computational Systems Biotechnology, Lausanne, Switzerland.ORCID http://orcid.org/0000-0001-6432-4694
Wout van HelvoirtDepartment of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Oslo, Norway.ORCID http://orcid.org/0000-0002-9143-9726
Christopher S HenryArgonne National Laboratory, Lemont, IL, USA.
Henning HermjakobEuropean Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, UK.ORCID http://orcid.org/0000-0001-8479-0262
Markus J HerrgårdNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0003-2377-9929
Ali KaafaraniNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0002-2805-310X
Hyun Uk KimDepartment of Chemical and Biomolecular Engineering (BK21 Plus Program), BioProcess Engineering Research Center, BioInformatics Research Center, Institute for the BioCentury, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Korea.ORCID http://orcid.org/0000-0001-7224-642X
Zachary KingDepartment of Bioengineering, University of California, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-1238-1499
Steffen KlamtAnalysis and Redesign of Biological Networks, Max Planck Institute for Dynamics of Complex Technical Systems Magdeburg, Magdeburg, Germany.ORCID http://orcid.org/0000-0003-2563-7561
Edda KlippTheoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0002-0567-7075
Jasper J KoehorstDepartment of Agrotechnology and Food Sciences, Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.ORCID http://orcid.org/0000-0001-8172-8981
Matthias KönigTheoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1725-179X
Meiyappan LakshmananBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID http://orcid.org/0000-0003-2356-3458
Dong-Yup LeeBioprocessing Technology Institute, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Sang Yup LeeNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0003-0599-3091
Sunjae LeeScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-6428-5936
Nathan E LewisDepartment of Bioengineering, University of California, La Jolla, CA, USA.
Filipe LiuArgonne National Laboratory, Lemont, IL, USA.
Hongwu MaKey Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, P.R. China.
Daniel MachadoStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.
Radhakrishnan MahadevanDepartment of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-1270-9063
Paulo MaiaSilicoLife Lda., Braga, Portugal.ORCID http://orcid.org/0000-0002-0848-8683
Adil MardinogluScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4254-6090
Gregory L MedlockDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Jonathan M MonkDepartment of Bioengineering, University of California, La Jolla, CA, USA.
Jens NielsenNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0002-9955-6003
Lars Keld NielsenNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0001-8191-3511
Juan NogalesDepartment of Systems Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid, Spain.ORCID http://orcid.org/0000-0002-4961-0833
Intawat NookaewChalmers University of Technology, Department of Biology and Biological Engineering, Division of Systems and Synthetic Biology, Göteborg, Sweden.
Bernhard O PalssonNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.ORCID http://orcid.org/0000-0003-2357-6785
Jason A PapinDepartment of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.
Kiran R PatilStructural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.ORCID http://orcid.org/0000-0002-6166-8640
Mark PoolmanOxford Brookes University, Oxford, UK.ORCID http://orcid.org/0000-0002-3972-5418
Nathan D PriceInstitute for Systems Biology, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-4157-0267
Osbaldo Resendis-AntonioHuman Systems Biology Laboratory, Instituto Nacional de Medicina Genomica & Coordinación de la Investigación Científica-Red de Apoyo a la Investigación, UNAM, Mexico City, Mexico.
Anne RichelleDepartment of Pediatrics and Novo Nordisk Foundation Center for Biosustainability, University of California, San Diego School of Medicine, La Jolla, CA, USA.
Isabel RochaCentre of Biological Engineering, University of Minho, Braga, Portugal.
Benjamín J SánchezNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark.
Peter J SchaapDepartment of Agrotechnology and Food Sciences, Laboratory of Systems and Synthetic Biology, Wageningen University & Research, Wageningen, the Netherlands.ORCID http://orcid.org/0000-0002-4346-6084
Rahuman S Malik SheriffEuropean Bioinformatics Institute, European Molecular Biology Laboratory (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, UK.
Saeed ShoaieScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-5834-4533
Nikolaus SonnenscheinNovo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark. niso@biosustain.dtu.dk.ORCID http://orcid.org/0000-0002-7581-4936
Bas TeusinkSystems Biology Lab, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-3929-0423
Paulo VilaçaSilicoLife Lda., Braga, Portugal.
Jon Olav VikDepartment of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Oslo, Norway.ORCID http://orcid.org/0000-0002-7778-4515
Judith A H WodkeTheoretical Biophysics, Humboldt-Universität zu Berlin, Berlin, Germany.
Joana C XavierInstitute for Molecular Evolution, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.ORCID http://orcid.org/0000-0001-9242-8968
Qianqian YuanKey Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, P.R. China.
Maksim ZakhartsevDepartment of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Cheng ZhangScience for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3721-8586
Funding
VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9MUnderstanding the Negative Prognostic Impact of Intraosseous Focal Lesions in Multiple MyelomaP20GM125503 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI Sanja Novak · 2018 to 2026
$23.0MContinued Support of Essential SBML Software and Community ResourcesR01GM070923 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI HUCKA, MICHAEL · 2004 to 2018
$8.0MUnraveling the mammalian secretory pathway through systems biology and algorithm developmentR35GM119850 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LEWIS, NATHAN ENOCH · 2016 to 2025
$4.3MSystems biology of microbe-mediated glucosinolate bioconversion in inflammatory bowel diseaseR01AT010253 · NCCIH · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON · 2018 to 2021
$2.0MMapping and predicting metabolic fluxes between the ileal microbiome and hostR01GM108501 · NIGMS · UNIVERSITY OF VIRGINIA · PI PAPIN, JASON · 2014 to 2017
$1.4MTransdisciplinary Big Data Science Training at UVaT32LM012416 · NLM · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, LOUGHRAN, THOMAS P. · 2016 to 2020
$1.3MMedical Research Council MC_UU_00025/11NCCIH NIH HHS R01 AT010253NCI NIH HHS P30 CA023100NIGMS NIH HHS P20 GM125503NIGMS NIH HHS R01 GM070923NIGMS NIH HHS R01 GM108501NIGMS NIH HHS R35 GM119850NLM NIH HHS T32 LM012416
Abstract
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Metabolic Networks and PathwaysComputational BiologyGenomeModels, BiologicalMolecular Sequence AnnotationWorkflow
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