ArticleNature plants2020
An ancestral signalling pathway is conserved in intracellular symbioses-forming plant lineages.
Article in Nature plants, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.
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Who cites it
103 citing papers in PubMed, 245 citations in OpenAlex.
- Review
- Paralogous LRR receptor kinases confer symbiosis specificity between arbuscular mycorrhizal and root nodule symbioses in Lotus japonicus.The New phytologist · 2026Article
- A simple cell-cycle control system in Marchantia polymorpha provides a framework for understanding plant cell proliferation.The Plant cell · 2026Article
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- Epigenetic regulation of mycorrhizal symbioses: from plastic responses to transgenerational legacies.The New phytologist · 2026Review
- Symbiosis signalling genes negatively regulate root responses to salt stress via the CCaMK-IPD3 module in Medicago truncatula.Journal of experimental botany · 2026Article
- An NSP2-MYB module orchestrates flavonoid biosynthesis and nodule symbiosis.Current biology : CB · 2026Article
- Contribution of orchids to the carbon budget of fungi in germinating seeds of Gymnadenia conopsea.Science China. Life sciences · 2026Article
- Molecular mechanisms modulating beneficial plant root-microbe interactions: What's common?Plant communications · 2026Review
- Decoding dark septate endophyte symbiosis: a functional and ecological perspective.FEMS microbiology reviews · 2026Review
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- Gibberellin biosynthesis inFrontiers in plant science · 2026Article
- Non-seed plant research in the spotlight.Biology open · 2025Article
- Self-fertilizing crops : Plant Biotech's Hardest, Most Rewarding Task.EMBO reports · 2025Article
- Convergent losses of arbuscular mycorrhizal symbiosis in carnivorous plants.The New phytologist · 2025Article
- Exploring fern pathosystems and immune receptors to bridge gaps in plant immunity.BMC biology · 2025Article
- Bryophytes hold a larger gene family space than vascular plants.Nature genetics · 2025Article
- Overexpression of miR399d impairs arbuscular mycorrhizal symbiosis in tomato.Plant biotechnology journal · 2025Article
43 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
18 authors at 6 institutions in 6 countries.
Funding
Abstract
Plants are the foundation of terrestrial ecosystems, and their colonization of land was probably facilitated by mutualistic associations with arbuscular mycorrhizal fungi. Following this founding event, plant diversification has led to the emergence of a tremendous diversity of mutualistic symbioses with microorganisms, ranging from extracellular associations to the most intimate intracellular associations, where fungal or bacterial symbionts are hosted inside plant cells. Here, through analysis of 271 transcriptomes and 116 plant genomes spanning the entire land-plant diversity, we demonstrate that a common symbiosis signalling pathway co-evolved with intracellular endosymbioses, from the ancestral arbuscular mycorrhiza to the more recent ericoid and orchid mycorrhizae in angiosperms and ericoid-like associations of bryophytes. By contrast, species forming exclusively extracellular symbioses, such as ectomycorrhizae, and those forming associations with cyanobacteria, have lost this signalling pathway. This work unifies intracellular symbioses, revealing conservation in their evolution across 450 million yr of plant diversification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.