Evidence map›Paper›PMID 32123347›Full record

ArticleNature microbiology2020

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2.

Coronaviridae Study Group of the International Committee on Taxonomy of Viruses

11 registry-linked trialsAbstract readConsensus Statement
In one paragraph

Article in Nature microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 11 registered trials, which are not on this map. Cited by 3,818 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3,818citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04403672 unknown statusnot on this map

Performance Evaluation of RealDetect™ COVID-19 RT-PCR Kit for the Detection of SARS-CoV-2 Virus

Typeobservational_patient_registrySponsorBangladesh Medical Research Council (BMRC)Ran2020 to 2020Enrolled120ConditionsHigh Sensitivity and Specificity (With 95% Confidence Interval) of RealDetect™ COVID-19 RT-PCR KitArmsperformance evaluation study of RealDetect RT-PCR Kit for COVID-19 detection
NCT04516811 phase3terminatednot on this map

A Prospective, Randomized, Placebo-controlled, Double-blinded, Phase III Clinical Trial of the Therapeutic Use of Convalescent Plasma in the Treatment of Patients With Moderate to Severe COVID-19

TypeinterventionalSponsorSouth African National Blood ServiceRan2020 to 2022Enrolled102ConditionsCOVID-19, SARS-CoV-2 Infection, Severe Acute Respiratory Syndrome Coronavirus 2ArmsCOVID-19 convalescent plasma (CCP) plus standard of care (SOC), Standard of care (SOC) plus placebo
NCT04625725 phase3completednot on this map

A Phase III Randomized, Double-blind, Placebo-controlled, Multi-center Study in Adults to Determine the Safety and Efficacy of AZD7442, a Combination Product of Two Monoclonal Antibodies (AZD8895 and AZD1061), for Pre-exposure Prophylaxis of COVID-19.

TypeinterventionalSponsorAstraZenecaRan2020 to 2023Enrolled5,197ConditionsCOVID-19ArmsAZD7442, Placebo
NCT04625972 phase3completednot on this map

A Phase III Randomized, Double-blind, Placebo-controlled, Multi-center Study in Adults to Determine the Safety and Efficacy of AZD7442, a Combination Product of Two Monoclonal Antibodies (AZD8895 and AZD1061), for Post-exposure Prophylaxis of COVID-19

TypeinterventionalSponsorAstraZenecaRan2020 to 2022Enrolled1,131ConditionsCOVID-19ArmsAZD7442, Placebo
NCT04780152 phase2 / phase3unknown statusnot on this mapstarted 2021, after this paper: background citation

Assessment of Efficacy and Safety of Anodal Transcranial Direct Current Stimulation (TDCS) in Pediatric and Teenage Patients With Major Depressive Disorder During COVID-19 Pandemics

TypeinterventionalSponsorEl Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco SuarezRan2021 to 2022Enrolled172ConditionsMajor Depressive DisorderArmsTranscranial Direct Current Stimulation, Placebo-simulation of transcranial direct current stimulation, Fluoxetine Tablets
NCT04822402 unknown statusnot on this mapstarted 2021, after this paper: background citation

COVID-19 Among Pregnant Women in Isolation and Women Hospitals in Assiut

Typeobservational_patient_registrySponsorAssiut UniversityRan2021 to 2022Enrolled50ConditionsCovid-19 in Pregnancy
NCT04904445 completednot on this mapstarted 2021, after this paper: background citation

COVID-19 Antibody Responses In Cystic Fibrosis

TypeobservationalSponsorErasmus Medical CenterRan2021 to 2024Enrolled40ConditionsCystic Fibrosis
NCT05435443 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison of Two Respiratory Physiotherapy Treatments in Postcovid-19 Patients. Randomiced Clinical Trial

TypeinterventionalSponsorUniversidad Católica de ÁvilaRan2022 to 2022Enrolled200ConditionsCOVID-19, Respiratory Distress SyndromeArmsPowerBreathe and PEP Therosold tools
NCT05450120 naunknown statusnot on this map

Neuromuscular Electrical Stimulation and Functional Rehabilitation Protocol in Critically Ill Patients With SARS-CoV-2 Variants in ICUs With Limited Resources: A Randomized Clinical Trial

TypeinterventionalSponsorUniversidade Federal de Sao CarlosRan2020 to 2022Enrolled88ConditionsCOVID-19 Acute Respiratory Distress SyndromeArmsFunctional Rehabilitation, Neuromuscular Electrical Stimulation
NCT06304623 phase1completednot on this map

The Role of Cellular Therapy With SVF Cells (Stromal Vascular Fraction) of Adipose Tissue Origin in the Treatment of Pulmonary Fibrosis Post COVD-19

TypeinterventionalSponsorMichael H CarstensRan2020 to 2024Enrolled40ConditionsPulmonary FibrosisArmsAutologous adipose-derived SVF IV administration
NCT06597370 completednot on this mapstarted 2021, after this paper: background citation

Immunogenicity Induced by COVID-19 Vaccines in Mexican Population: mRNA Expression for IgG Anti-spike

Typeobservational_patient_registrySponsorNational Polytechnic Institute, MexicoRan2021 to 2021Enrolled80ConditionsCOVID-19 VaccineArmsGene expression mRNA of IgG anti-spike
3 · Its place in the literature

Who cites it

3,818 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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3,758 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Coronaviridae Study Group of the International Committee on Taxonomy of Viruses

Funding

SARS-CoV Proteins in Heterologous Viral InfectionP01AI060699 · NIAID · UNIVERSITY OF IOWA · PI PERLMAN, STANLEY · 2004 to 2021
$21.5M
Mechanisms of viral proteases in coronavirus replication and pathogenesisR01AI085089 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI BAKER, SUSAN C., MESECAR, ANDREW D · 2010 to 2019
$6.8M
Role of eicosanoids in pathogenic human CoV infectionsR01AI129269 · NIAID · UNIVERSITY OF IOWA · PI Stanley Perlman · 2016 to 2026
$4.7M
NIAID NIH HHS P01 AI060699NIAID NIH HHS R01 AI085089NIAID NIH HHS R01 AI129269
6 · The paper itself

Abstract

The present outbreak of a coronavirus-associated acute respiratory disease called coronavirus disease 19 (COVID-19) is the third documented spillover of an animal coronavirus to humans in only two decades that has resulted in a major epidemic. The

Indexed as

AnimalsBetacoronavirusClassificationCoronaviridaeCoronavirus InfectionsCOVID-19Genetic VariationGenome, ViralHumansNidoviralesOpen Reading FramesPandemicsPhylogenyPneumonia, ViralSARS-CoV-2Severe Acute Respiratory Syndrome

Identifiers

PMID32123347
PMCPMC7095448

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

and 5 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.