Trial reportScientific reports2020
Structural Alterations in Large-scale Brain Networks and Their Relationship with Sleep Disturbances in the Adolescent Population.
Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Structural Brain Correlates of Insufficient Sleep in Adolescents: A Narrative Review of MRI Evidence.Children (Basel, Switzerland) · 2026Review
- Sleep as a moderator of adolescent brain development-evidence from a longitudinal MRI study.Sleep · 2026Article
- Age and Sex Moderate the Effects of Sleep Quality on Resting-State Functional Connectivity in the Salience and Default Mode Network.Research square · 2025Article
- J-Shaped Association Between Sleep Timing and Suicidal Ideation: A Nationwide Cross-Sectional Study.Nature and science of sleep · 2025Article
- Association between sleep problems and impulsivity mediated through regional homogeneity abnormalities in male methamphetamine abstainers.Brain imaging and behavior · 2024Article
- The associations among sleep-related difficulties, anxiety, and error-related brain activity in youth.Biological psychology · 2024Article
- Bibliometric Analysis of Brain Stimulation Technologies in Sleep Disorders.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers.Neuroimage. Reports · 2024Article
- Socioeconomic disparities in sleep duration are associated with cortical thickness in children.Brain and behavior · 2023Article
- Cerebellar Gray Matter Volume and its Role in Executive Function, and Attention: Sex Differences by Age in Adolescents.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2022Article
- Resting-state functional connectivity of the sensory/somatomotor network associated with sleep quality: evidence from 202 young male samples.Brain imaging and behavior · 2022Article
- Shorter Duration and Lower Quality Sleep Have Widespread Detrimental Effects on Developing Functional Brain Networks in Early Adolescence.Cerebral cortex communications · 2022Article
- Article
- The Association Between Hippocampal Volume and Level of Attention in Children and Adolescents.Frontiers in systems neuroscience · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although sleep disturbances are highly prevalent in adolescents, neuroimaging evidence on the effects of sleep disturbances on their developing brains remains limited. Therefore, we explored gray matter volumes (GMVs) at the whole-brain level and investigated their relationship to sleep disturbances in a sample of Korean adolescents in the general population. We recruited participants from one middle school and high school. All participants and their legal guardians gave informed consent before participating in our study. We used component 5 of the Pittsburgh Sleep Quality Index to measure sleep disturbances and conducted a voxel-based morphometry-DARTEL procedure to measure GMVs. We performed partial correlation analyses to examine whether the GMVs were associated with sleep disturbances. A total of 56 adolescents participated in this study. Our results revealed that GMVs in multiple global regions were negatively correlated with sleep disturbances. Moreover, most of these identified regions belong to large-scale brain networks categorized by functional neuroimaging studies. We found an association between regional GMVs in multiple global regions involved in large-scale networks and the severity of sleep disturbances in the adolescent population. Based on this evidence and previous neuroimaging evidence, we suggest that structural alterations in the networks may be linked to sleep disturbances.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.