Evidence map›Paper›PMID 32123111›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Sylvia E J Fischer, Gary Ruvkun

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
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  6. ADARs mediate distinct RNA editing activity and gene regulation in thebioRxiv : the preprint server for biology · 2025
    Article
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  8. Review
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  12. Intraspecific variation in the duration of epigenetic inheritance.bioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. Article
  15. The importance of IP6 for ADAR RNA-editing enzymes and antiviral defense.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sylvia E J FischerDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114; sylvia.fischer@childrens.harvard.edu ruvkun@molbio.mgh.harvard.edu.ORCID 0000-0003-4290-0093
Gary RuvkunDepartment of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114; sylvia.fischer@childrens.harvard.edu ruvkun@molbio.mgh.harvard.edu.
Harvard University · US

Funding

CONTROL OF THE C ELEGANS LINEAGE BY HETEROCHRONIC GENESR01GM044619 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI GARY B RUVKUN · 1991 to 2026
$14.5M
NIGMS NIH HHS R01 GM044619
6 · The paper itself

Abstract

Endogenous retroviruses and long terminal repeat (LTR) retrotransposons are mobile genetic elements that are closely related to retroviruses. Desilenced endogenous retroviruses are associated with human autoimmune disorders and neurodegenerative diseases.

Indexed as

RNA InterferenceAdenosine DeaminaseAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDNA HelicasesDNA, ViralEndogenous RetrovirusesEndoplasmic Reticulum StressGene Expression Regulation, ViralGenes, ViralHost Microbial InteractionsHumansRetroelementsRNA, Double-StrandedRNA, ViralAdenosine DeaminaseCaenorhabditis elegans ProteinsDNA HelicasesDNA, ViralERI-6 protein, C elegansERI-7 protein, C elegansRetroelementsRNA, Double-StrandedRNA, ViralADARretrotransposonRNA interferenceRNA silencing

Identifiers

PMID32123111
PMCPMC7084138
OpenAlexW3010537466

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.