Evidence map›Paper›PMID 32122896›Full record

ArticleAntimicrobial agents and chemotherapy2020

Insecticidal Activity of Doxycycline against the Common Bedbug.

Jose E Pietri, Dangsheng Liang

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jose E PietriUniversity of South Dakota, Sanford School of Medicine, Division of Basic Biomedical Sciences, South Dakota, USA Jose.Pietri@usd.edu.
Dangsheng LiangApex Bait Technologies, Inc., Santa Clara, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an ongoing need for safe and effective anti-bedbug compounds. Here, we tested the toxicity of three antimicrobial agents against bedbugs when administered orally. We reveal that doxycycline has direct insecticidal activity at 250 μg/ml (0.025%) that is particularly strong against immature bedbugs and appears to be independent of antimicrobial activity. Future studies to determine the mechanisms behind this property could be useful for the development of orally active insecticides or anti-bedbug therapeutics.

Indexed as

AnimalsAnti-Bacterial AgentsBedbugsDoxycyclineInsecticidesPenicillinsRifampinSymbiosisWolbachiaAnti-Bacterial AgentsDoxycyclineInsecticidesPenicillinsRifampinbedbugCimexdoxycyclineinsecticidalinsecticidetoxicity

Identifiers

PMID32122896
PMCPMC7179621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.