Evidence map›Paper›PMID 32122439›Full record

ArticlePsychological medicine2021

Social disadvantage, linguistic distance, ethnic minority status and first-episode psychosis: results from the EU-GEI case-control study.

Hannah E Jongsma, Charlotte Gayer-Anderson, Ilaria Tarricone, Eva Velthorst, Els van der Ven, Diego Quattrone, Marta di Forti, EU-GEI WP2 Group, Paulo Rossi Menezes, Christina Marta Del-Ben and 18 more

Open access · hybridAbstract read
In one paragraph

Article in Psychological medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
22.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  3. The ethnic density effect in psychosis: a systematic review and multilevel meta-analysis.The British journal of psychiatry : the journal of mental science · 2021
    Pooled it
  4. Language proficiency and mental disorders among migrants: A systematic review.European psychiatry : the journal of the Association of European Psychiatrists · 2021
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 16 institutions in 7 countries.

Hannah E JongsmaPsyLife Group, Division of Psychiatry, UCL, London, England.ORCID 0000-0001-6346-5903
Charlotte Gayer-AndersonDepartment of Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
Ilaria TarriconeTranscultural Psychosomatic Team (BoTPT), Department of Surgical and Medical Sciences, Bologna University, Bologna, Italy.
Eva VelthorstDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Els van der VenDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Diego QuattroneDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
Marta di FortiDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
EU-GEI WP2 Group
Paulo Rossi MenezesDepartment of Preventive Medicine, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil.
Christina Marta Del-BenDivision of Psychiatry, Department of Neuroscience and Behaviour, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Celso ArangoDepartment of Child and Adolescent Psychiatry, Hospital General Universitario Gregorio Marañón, School of Medicine, Universidad Complutense, Investigación Sanitaria del Hospital Gregorio Marañón, Madrid, Spain.
Antonio LasalviaSection of Psychiatry, Azienda Ospedaliera Universitaria Integra di Verona, Verona, Italy.
Domenico BerardiDepartment of Biomedical and Neuro-motor Sciences, Psychiatry Unit, Alma Mater Studiorum Università di Bologna, 40126Bologna, Italy.
Caterina La CasciaUnit of Psychiatry, 'P. Giaccone' General Hospital, Palermo, Italy.
Julio BobesDepartment of Medicine, Psychiatry Area, School of Medicine, Universidad de Oviedo, Centro de Investigación Biomédica en Red de Salud Mental, Instituto Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.
Miguel BernardoBarcelona Clinic Schizophrenia Unit, Department of Medicine, Neuroscience Institute, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Salud Mental, Barcelona, Spain.
Julio SanjuánDepartment of Psychiatry, School of Medicine, Universidad de Valencia, Centro de Investigación Biomédica en Red de Salud Mental, Valencia, Spain.
Jose Luis SantosDepartment of Psychiatry, Servicio de Psiquiatría Hospital 'Virgen de la Luz', Cuenca, Spain.
Manuel ArrojoDepartment of Psychiatry, Psychiatric Genetic Group, Instituto de Investigación Sanitaria de Santiago de Compostela, Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Lieuwe de HaanEarly Psychosis Section, Department of Psychiatry, Amsterdam UMC, location AMC, Amsterdam, The Netherlands.
Andrea TortelliEtablissement Public de Santé Maison Blanche, Paris, France.
Andrei SzökeInstitut National de la Santé et de la Recherche Médicale, U955, Créteil, France.
Robin M MurrayDepartment of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
Bart P RuttenDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.
Jim van OsDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University Medical Centre, Maastricht, The Netherlands.
Craig MorganDepartment of Health Services and Population Research, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, England.
Peter B JonesDepartment of Psychiatry, University of Cambridge, Cambridge, England.
James B KirkbridePsyLife Group, Division of Psychiatry, UCL, London, England.
King's College London · GBUniversidade de São Paulo · BRAmsterdam University Medical Centers · NLInserm · FRNational Health Service · GBUniversidad de Oviedo · ESUniversitat de València · ESAzienda Ospedaliera Universitaria Integrata Verona · ITAzienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo · ITComplejo Hospitalario Universitario de Santiago · ESHospital General Universitario Gregorio Marañón · ESHospital Virgen de la Luz · ESMaastricht University Medical Centre · NLUniversity College London · GBUniversity of Bologna · ITUniversity of Cambridge · GB

Funding

Department of HealthWellcome Trust 101272/Z/13/Z
6 · The paper itself

Abstract

backgroundEthnic minority groups in Western countries face an increased risk of psychotic disorders. Causes of this long-standing public health inequality remain poorly understood. We investigated whether social disadvantage, linguistic distance and discrimination contributed to these patterns.

methodsWe used case-control data from the EUropean network of national schizophrenia networks studying Gene-Environment Interactions (EU-GEI) study, carried out in 16 centres in six countries. We recruited 1130 cases and 1497 population-based controls. Our main outcome measure was first-episode ICD-10 psychotic disorder (F20-F33), and exposures were ethnicity (white majority, black, mixed, Asian, North-African, white minority and other), generational status, social disadvantage, linguistic distance and discrimination. Age, sex, paternal age, cannabis use, childhood trauma and parental history of psychosis were included as a priori confounders. Exposures and confounders were added sequentially to multivariable logistic models, following multiple imputation for missing data.

resultsParticipants from any ethnic minority background had crude excess odds of psychosis [odds ratio (OR) 2.03, 95% confidence interval (CI) 1.69-2.43], which remained after adjustment for confounders (OR 1.61, 95% CI 1.31-1.98). This was progressively attenuated following further adjustment for social disadvantage (OR 1.52, 95% CI 1.22-1.89) and linguistic distance (OR 1.22, 95% CI 0.95-1.57), a pattern mirrored in several specific ethnic groups. Linguistic distance and social disadvantage had stronger effects for first- and later-generation groups, respectively.

conclusionSocial disadvantage and linguistic distance, two potential markers of sociocultural exclusion, were associated with increased odds of psychotic disorder, and adjusting for these led to equivocal risk between several ethnic minority groups and the white majority.

Indexed as

Communication BarriersAdolescentAdultBlack PeopleCase-Control StudiesEthnic and Racial MinoritiesEthnicityEuropeFemaleGene-Environment InteractionHealth Status DisparitiesHumansMaleMiddle AgedOdds RatioPsychotic DisordersDiscriminationepidemiologyethnicitypsychotic disorderssocial disadvantage

Identifiers

PMID32122439
PMCPMC8311819
OpenAlexW3009194698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.