Evidence map›Paper›PMID 32122176›Full record

ArticleExpert opinion on drug discovery2020

Can we mimic skeletal muscles for novel drug discovery?

Torie Broer, Alastair Khodabukus, Nenad Bursac

Abstract readEditorial
In one paragraph

Article in Expert opinion on drug discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Current Strategies for the Regeneration of Skeletal Muscle Tissue.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Torie BroerDepartment of Biomedical Engineering, Duke University , Durham, NC, USA.
Alastair KhodabukusDepartment of Biomedical Engineering, Duke University , Durham, NC, USA.
Nenad BursacDepartment of Biomedical Engineering, Duke University , Durham, NC, USA.

Funding

Vascular, Cardiac, and Lung Alveolar Human Microphysiological Systems for SARS-CoV-2 Drug ScreeningUH3TR002142 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2019 to 2021
$4.0M
University Training Program in Biomolecular and Tissue EngineeringT32GM144291 · NIGMS · DUKE UNIVERSITY · PI Charles A. Gersbach, Tatiana Segura · 2022 to 2026
$2.6M
Systemic Inflammation in Microphysiological Models of Muscle and Vascular DiseaseUG3TR002142 · NCATS · DUKE UNIVERSITY · PI TRUSKEY, GEORGE A · 2017 to 2018
$2.1M
Microphysiological Human Tissue Systems for Monitoring of Genome Editing OutcomesU01HL156348 · NHLBI · DUKE UNIVERSITY · PI BURSAC, NENAD, GERSBACH, CHARLES A. · 2020 to 2022
$2.0M
Muscle-macrophage constructs for skeletal muscle repairR01AR070543 · NIAMS · DUKE UNIVERSITY · PI BURSAC, NENAD · 2016 to 2020
$1.9M
Translational studies of GAA deficiency in bioengineered human muscleR01AR065873 · NIAMS · DUKE UNIVERSITY · PI BURSAC, NENAD, KOEBERL, DWIGHT D · 2013 to 2017
$1.8M
Microphysiological Human Tissue Systems for Monitoring of Genome Editing OutcomesU01EB028901 · NIBIB · DUKE UNIVERSITY · PI BURSAC, NENAD, GERSBACH, CHARLES A. · 2019 to 2019
$668k
NCATS NIH HHS UG3 TR002142NCATS NIH HHS UH3 TR002142NHLBI NIH HHS U01 HL156348NIAMS NIH HHS R01 AR065873NIAMS NIH HHS R01 AR070543NIBIB NIH HHS U01 EB028901NIGMS NIH HHS T32 GM144291
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBiomimeticsDrug DiscoveryHumansMuscle, SkeletalTissue Engineeringdrug developmentdystrophySkeletal muscletissue engineeringtoxicity

Identifiers

PMID32122176
PMCPMC7260101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.