Evidence map›Paper›PMID 32121654›Full record

ArticleToxins2020

Inhibitory Effects of a Reengineered Anthrax Toxin on Canine Oral Mucosal Melanomas.

Adriana Tomoko Nishiya, Marcia Kazumi Nagamine, Ivone Izabel Mackowiak da Fonseca, Andrea Caringi Miraldo, Nayra Villar Scattone, José Luiz Guerra, José Guilherme Xavier, Mário Santos, Cristina Oliveira Massoco de Salles Gomes, Jerrold Michael Ward and 4 more

Open access · goldAbstract readClinical Trial, Veterinary
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  5. Review
  6. RAGE Signaling in Melanoma Tumors.International journal of molecular sciences · 2020
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Adriana Tomoko NishiyaDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Marcia Kazumi NagamineDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Ivone Izabel Mackowiak da FonsecaDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Andrea Caringi MiraldoDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Nayra Villar ScattoneDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
José Luiz GuerraDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
José Guilherme XavierRous Animal Pathology, Private Veterinary Pathology Services. Av. Lacerda Franco 127, Sao Paulo 01536-000, SP, Brazil.
Mário SantosRous Animal Pathology, Private Veterinary Pathology Services. Av. Lacerda Franco 127, Sao Paulo 01536-000, SP, Brazil.
Cristina Oliveira Massoco de Salles GomesDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Jerrold Michael WardGlobal Vet Pathology, Montgomery Village, MD 20886, USA.
Shihui LiuAging Institute and Division of Infectious Diseases, Department of Medicine, University of Pittsburg, Pittsburgh, PA 15261, USA.
Stephen Howard LepplaMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Thomas Henrik BuggeProteases & Tissue Remodeling Section, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD 20892, USA.
Maria Lucia Zaidan DagliDepartment of Pathology, School of Veterinary Medicine and Animal Science, University of Sao Paulo, Sao Paulo 05508-270, SP, Brazil.
Universidade de São Paulo · BRGlobal VetPathology · USNational Institute of Dental and Craniofacial Research · USNational Institutes of Health · USPittsburg State University · US

Funding

Cell surface serine proteases in development, tissue repair, and malignancyZIADE000699 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI BUGGE, THOMAS H · 2009 to 2025
$34.1M
Vaccines and Therapeutics for AnthraxZIAAI000929 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LEPPLA, STEPHEN · 2009 to 2025
$15.9M
Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/16776-3
6 · The paper itself

Abstract

Canine oral mucosal melanomas (OMM) are the most common oral malignancy in dogs and few treatments are available. Thus, new treatment modalities are needed for this disease.

Indexed as

AnimalsAntigens, BacterialAntineoplastic AgentsBacterial ToxinsDog DiseasesDogsFemaleMaleMatrix Metalloproteinase 2MelanomaMouth MucosaMouth NeoplasmsProtein EngineeringReceptors, Urokinase Plasminogen ActivatorTissue Inhibitor of Metalloproteinase-2Urokinase-Type Plasminogen Activatoranthrax toxinAntigens, BacterialAntineoplastic AgentsBacterial ToxinsMatrix Metalloproteinase 2Receptors, Urokinase Plasminogen ActivatorTissue Inhibitor of Metalloproteinase-2Urokinase-Type Plasminogen ActivatoranthraxBacillus anthracisdogoral melanomatoxin

Identifiers

PMID32121654
PMCPMC7150776
OpenAlexW3010009737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.