Evidence map›Paper›PMID 32121471›Full record

ArticleCancers2020

Detection of Glioblastoma Subclinical Recurrence Using Serial Diffusion Tensor Imaging.

Yan Jin, James W Randall, Hesham Elhalawani, Karine A Al Feghali, Andrew M Elliott, Brian M Anderson, Lara Lacerda, Benjamin L Tran, Abdallah S Mohamed, Kristy K Brock and 2 more

Abstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Predicting glioblastoma progression using MR diffusion tensor imaging: A systematic review.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yan JinDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
James W RandallDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Hesham ElhalawaniDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Karine A Al FeghaliDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Andrew M ElliottDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Brian M AndersonDepartment of Imaging Physics, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Lara LacerdaDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Benjamin L TranDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Abdallah S MohamedDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Kristy K BrockDepartment of Imaging Physics, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Clifton D FullerDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Caroline ChungDepartment of Radiation Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672University of Texas MD Anderson Cancer Center P30CA01667University of Texas MD Anderson Cancer Center ROSI Grant
6 · The paper itself

Abstract

Glioblastoma is an aggressive brain tumor with a propensity for intracranial recurrence. We hypothesized that tumors can be visualized with diffusion tensor imaging (DTI) before they are detected on anatomical magnetic resonance (MR) images. We retrospectively analyzed serial MR images from 30 patients, including the DTI and T1-weighted images at recurrence, at 2 months and 4 months before recurrence, and at 1 month after radiation therapy. The diffusion maps and T1 images were deformably registered longitudinally. The recurrent tumor was manually segmented on the T1-weighted image and then applied to the diffusion maps at each time point to collect mean FA, diffusivities, and neurite density index (NDI) values, respectively. Group analysis of variance showed significant changes in FA (

Indexed as

diffusion tensor imagingglioblastomaMRIradiation therapyrecurrence

Identifiers

PMID32121471
PMCPMC7139975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.