Evidence map›Paper›PMID 32121389›Full record

ArticleMetabolites2020

Local Phenomena Shape Backyard Soil Metabolite Composition.

Tra D Nguyen, Mahbobeh Lesani, Ines Forrest, Yunpeng Lan, Danya A Dean, Quentin M R Gibaut, Yanting Guo, Ekram Hossain, Marcela Olvera, Hannah Panlilio and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tra D NguyenDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Mahbobeh LesaniDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, OK 73019, USA.
Ines ForrestDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Yunpeng LanDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Danya A DeanDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Quentin M R GibautDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Yanting GuoDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Ekram HossainDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.ORCID 0000-0002-0616-3420
Marcela OlveraDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Hannah PanlilioDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Adwaita R ParabDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, OK 73019, USA.
Chaoyi WuDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Jean A BernatchezSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0002-8309-1627
Robert H CichewiczDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.
Laura-Isobel McCallDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA.ORCID 0000-0002-1243-8953

Funding

College of Arts and Sciences, University of Oklahoma 122722501
6 · The paper itself

Abstract

Soil covers most of Earth's continental surface and is fundamental to life-sustaining processes such as agriculture. Given its rich biodiversity, soil is also a major source for natural product drug discovery from soil microorganisms. However, the study of the soil small molecule profile has been challenging due to the complexity and heterogeneity of this matrix. In this study, we implemented high-resolution liquid chromatography-tandem mass spectrometry and large-scale data analysis tools such as molecular networking to characterize the relative contributions of city, state and regional processes on backyard soil metabolite composition, in 188 soil samples collected from 14 USA States, representing five USA climate regions. We observed that region, state and city of collection all influence the overall soil metabolite profile. However, many metabolites were only detected in unique sites, indicating that uniquely local phenomena also influence the backyard soil environment, with both human-derived and naturally-produced (plant-derived, microbially-derived) metabolites identified. Overall, these findings are helping to define the processes that shape the backyard soil metabolite composition, while also highlighting the need for expanded metabolomic studies of this complex environment.

Indexed as

human activityLC-MS/MSmetabolomicsmolecular networkingnatural productssoil

Identifiers

PMID32121389
PMCPMC7143036

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.