Evidence map›Paper›PMID 32121332›Full record

ArticleMicroorganisms2020

Strategies to Prevent Biofilm Infections on Biomaterials: Effect of Novel Naturally-Derived Biofilm Inhibitors on a Competitive Colonization Model of Titanium by

Inés Reigada, Ramón Pérez-Tanoira, Jayendra Z Patel, Kirsi Savijoki, Jari Yli-Kauhaluoma, Teemu J Kinnari, Adyary Fallarero

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Biology and Pathogenesis ofMicroorganisms · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Inés ReigadaDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland.
Ramón Pérez-TanoiraDepartment of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, Kasarmikatu 11-13, 00029 HUS, Helsinki 00130, Finland.
Jayendra Z PatelDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland.
Kirsi SavijokiDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland.
Jari Yli-KauhaluomaDrug Research Program, Division of Pharmaceutical Chemistry and Technology, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland.
Teemu J KinnariDepartment of Otorhinolaryngology-Head and Neck Surgery, Helsinki University Hospital, University of Helsinki, Kasarmikatu 11-13, 00029 HUS, Helsinki 00130, Finland.
Adyary FallareroDrug Research Program, Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki 00790, Finland.
University of Helsinki · FI

Funding

H2020 Marie Skłodowska-Curie Actions 722467Jane ja Aatos Erkon Säätiö N/A
6 · The paper itself

Abstract

Biofilm-mediated infection is a major cause of bone prosthesis failure. The lack of molecules able to act in biofilms has driven research aimed at identifying new anti-biofilm agents via chemical screens. However, to be able to accommodate a large number of compounds, the testing conditions of these screenings end up being typically far from the clinical scenario. In this study, we assess the potential applicability of three previously discovered anti-biofilm compounds to be part of implanted medical devices by testing them on

Indexed as

biofilmbiomaterialsco-cultureimplanted devicesSaOS-2Staphylococcus aureus

Identifiers

PMID32121332
PMCPMC7143544
OpenAlexW2995461580

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.