Evidence map›Paper›PMID 32121305›Full record

ReviewInternational journal of molecular sciences2020

EGR1 Transcription Factor is a Multifaceted Regulator of Matrix Production in Tendons and Other Connective Tissues.

Emmanuelle Havis, Delphine Duprez

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
52.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 491 citations in OpenAlex.

  1. Pooled it
  2. Blocking the mCellular & molecular immunology · 2026
    Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. RNA interference to reduceMolecular vision · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Melatonin mitigates intervertebral disc degeneration by suppressing NLRP3 inflammasome activation via the EGR1/DDX3X pathway.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Emmanuelle HavisLaboratoire de Biologie du Développement, UMR7622, Institut Biologie Paris Seine, Sorbonne Université, CNRS, Inserm U1156, F75005 Paris, France.
Delphine DuprezLaboratoire de Biologie du Développement, UMR7622, Institut Biologie Paris Seine, Sorbonne Université, CNRS, Inserm U1156, F75005 Paris, France.
Centre National de la Recherche Scientifique · FR

Funding

Association Française contre les Myopathies 22234Fondation pour la Recherche Médicale DEQ20140329500
6 · The paper itself

Abstract

Although the transcription factor EGR1 is known as NGF1-A, TIS8, Krox24, zif/268, and ZENK, it still has many fewer names than biological functions. A broad range of signals induce

Indexed as

AnimalsConnective TissueEarly Growth Response Protein 1Extracellular MatrixFibrosisHumansModels, BiologicalTendonsEarly Growth Response Protein 1adipose tissuecollagenconnective tissuesEGR1extracellular matrixtendon

Identifiers

PMID32121305
PMCPMC7084410
OpenAlexW3010197333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.