Evidence map›Paper›PMID 32121289›Full record

ArticleInternational journal of molecular sciences2020

METTL3 Modulates Osteoclast Differentiation and Function by Controlling RNA Stability and Nuclear Export.

Di Li, Luhui Cai, Runsha Meng, Zhihui Feng, Qiong Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 90 citations in OpenAlex.

  1. WTAP Transcriptional Suppression by KLF9 Drives Osteoclastogenesis via MAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. mMolecular medicine reports · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. RNA mCell investigation · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. The Role of mRNA Modifications in Bone Diseases.International journal of biological sciences · 2025
    Review
  17. Epigenetic Mechanisms in Osteoporosis: Exploring the Power of mJournal of cellular and molecular medicine · 2025
    Review
  18. mBiomaterials translational · 2025
    Review
  19. Unveiling the dynamics and therapeutic potential of mInternational journal of biological sciences · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Di Li
Luhui Cai
Runsha MengGuanghua School of Stomatology & Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, 56 Ling Yuan Xi Road, Guangzhou 510055, China.
Zhihui FengGuanghua School of Stomatology & Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, 56 Ling Yuan Xi Road, Guangzhou 510055, China.
Qiong XuGuanghua School of Stomatology & Guangdong Provincial Key Laboratory of Stomatology, Sun Yat-sen University, 56 Ling Yuan Xi Road, Guangzhou 510055, China.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoclast differentiation and function are crucial for maintaining bone homeostasis and preserving skeletal integrity. N6-methyladenosine (m

Indexed as

Cell DifferentiationActive Transport, Cell NucleusAdenosineAnimalsBone ResorptionCell NucleusCell ProliferationGene Knockdown TechniquesMethyltransferasesMiceMice, Inbred C57BLModels, BiologicalNF-kappa BOsteoclastsOsteogenesisPhosphatidylinositol 3-KinasesAdenosineAtp6v0d2 protein, mouseMethyltransferasesMettl3 protein, mouseNF-kappa BN-methyladenosinePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktRANK LigandRNA-Binding ProteinsRNA, MessengerTNF Receptor-Associated Factor 6TRAF6 protein, mouseVacuolar Proton-Translocating ATPasesYTHDF2 protein, mouseMETTL3mRNA stabilityN6-methyladenosinenuclear exportosteoclast differentiation

Identifiers

PMID32121289
PMCPMC7084668
OpenAlexW3009468546

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.