Evidence map›Paper›PMID 32121233›Full record

Observational studyNutrients2020

Angiotensin Converting Enzyme (ACE): A Marker for Personalized Feedback on Dieting.

Shilpa Tejpal, Narinder Sanghera, Vijayalaxmi Manoharan, Joan Planas-Iglesias, Claire C Bastie, Judith Klein-Seetharaman

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genetic diet interactions ofFrontiers in nutrition · 2023
    Review
  7. The Association ofInternational journal of molecular sciences · 2022
    Article
  8. Article
  9. Observational
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shilpa TejpalSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Narinder SangheraSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Vijayalaxmi ManoharanSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Joan Planas-IglesiasSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Claire C BastieSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Judith Klein-SeetharamanSystems Biology and Biomedicine, Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
University of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiotensin Converting Enzyme (ACE) expression and activity is associated with obesity. ACE is a circulating factor that predicts sustained weight loss over a time frame of months. Here, we evaluate whether ACE might also be an early marker (over a 24-hour period) for weight loss. 32 participants (78% females; BMI 28.47 ± 4.87kg/m2) followed a 1200KCal diet with an optional daily (<250KCal) snack and were asked to use an in-house generated health platform to provide recordings of food intake, physical activity and urine collection time and volume. Following a day of dieting, ACE levels in urine negatively correlated with weight loss (

Indexed as

DietFeedbackBiomarkersBody Mass IndexHumansInsulinLactic AcidLife StylePeptidyl-Dipeptidase AWeight LossACE protein, humanBiomarkersInsulinLactic AcidPeptidyl-Dipeptidase AACEbiomarkersdietingobesitypersonalized feedbackweight loss

Identifiers

PMID32121233
PMCPMC7146434
OpenAlexW3010302115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.