Evidence map›Paper›PMID 32121223›Full record

ArticleNutrients2020

Modulation of Adhesion Process, E-Selectin and VEGF Production by Anthocyanins and Their Metabolites in an

Mirko Marino, Cristian Del Bo', Massimiliano Tucci, Dorothy Klimis-Zacas, Patrizia Riso, Marisa Porrini

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

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  17. Recent Progress inFrontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mirko MarinoUniversità degli Studi di Milano, Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, 20133 Milan, Italy.
Cristian Del Bo'Università degli Studi di Milano, Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, 20133 Milan, Italy.
Massimiliano TucciUniversità degli Studi di Milano, Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, 20133 Milan, Italy.
Dorothy Klimis-ZacasSchool of Food and Agriculture, University of Maine, Orono, ME 04469, USA.
Patrizia RisoUniversità degli Studi di Milano, Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, 20133 Milan, Italy.
Marisa PorriniUniversità degli Studi di Milano, Department of Food, Environmental and Nutritional Sciences, Division of Human Nutrition, 20133 Milan, Italy.
University of Milan · ITUniversity of Maine · US

Funding

DeFENS Piano di sostegno alla ricerca- Linea 2, azione A-grant number PSR2019 and 2018-CDELB".Mipaaft Italy; D.M. 8245/7303/2016),
6 · The paper itself

Abstract

The present study aims to evaluate the ability of peonidin and petunidin-3-glucoside (Peo-3-glc and Pet-3-glc) and their metabolites (vanillic acid; VA and methyl-gallic acid; MetGA), to prevent monocyte (THP-1) adhesion to endothelial cells (HUVECs), and to reduce the production of vascular cell adhesion molecule (VCAM)-1, E-selectin and vascular endothelial growth factor (VEGF) in a stimulated pro-inflammatory environment, a pivotal step of atherogenesis. Tumor necrosis factor-α (TNF-α; 100 ng mL

Indexed as

MetabolomeModels, BiologicalAnthocyaninsAtherosclerosisCell AdhesionCell DeathCell SurvivalE-SelectinGallic AcidGlucosidesHumansHuman Umbilical Vein Endothelial CellsSolubilityTHP-1 CellsVanillic AcidVascular Cell Adhesion Molecule-1AnthocyaninsE-SelectinGallic AcidGlucosidespeonidinpetunidin-3-glucosideVanillic AcidVascular Cell Adhesion Molecule-1Vascular Endothelial Growth Factor Aadhesion moleculesAnthocyanins and metabolitesendothelial cellsinflammationmonocytesvascular endothelial growth factor

Identifiers

PMID32121223
PMCPMC7146381
OpenAlexW3000112417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.