Evidence map›Paper›PMID 32121156›Full record

ReviewGenes2020

The Metabolization Profile of the

Luciana P C Leitão, Tatiane P Souza, Juliana C G Rodrigues, Marianne R Fernandes, Sidney Santos, Ney P C Santos

Abstract readReview
In one paragraph

Review in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Associations between SelectedMedicina (Kaunas, Lithuania) · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Genetic Variation ofFrontiers in pharmacology · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luciana P C LeitãoOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.
Tatiane P SouzaOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.
Juliana C G RodriguesOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.
Marianne R FernandesOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.
Sidney SantosOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.
Ney P C SantosOncology Research Center, Federal University of Pará, Belém, Pará 66073, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundthe

methodsa systematic literature review was conducted in three scientific publication platforms (Google Scholar, Science Direct, and Pubmed). The search was run using the keywords "CYP2D6 Amerindians" and "CYP2D6 native Americans".

resultsa total of 13 original papers met the inclusion criteria established for this study. All the papers presented frequencies of the different

conclusionthe metabolization profiles of the Amerindian populations reviewed in the present study do not diverge in any major way from those of other populations from around the world. Given the paucity of the data available on Amerindian populations, further research is required to better characterize the metabolization profile of these populations to ensure the development of adequate therapeutic strategies.

Indexed as

Genetics, PopulationAllelesCytochrome P-450 CYP2C19Cytochrome P-450 CYP2D6GenotypeHumansIndians, North AmericanPolymorphism, GeneticSouth AmericaCytochrome P-450 CYP2C19Cytochrome P-450 CYP2D6AmerindiansCYP2D6genetic polymorphismsmetabolization profileNative Americansphenotype

Identifiers

PMID32121156
PMCPMC7140882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.