Evidence map›Paper›PMID 32121066›Full record

Trial reportMarine drugs2020

Micro RNA Expression after Ingestion of Fucoidan; A Clinical Study.

Nuri Gueven, Kevin J Spring, Sandra Holmes, Kiran Ahuja, Raj Eri, Ah Young Park, J Helen Fitton

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nuri GuevenPharmacy, School of Medicine, University of Tasmania, Hobart, TAS 7001, Australia.ORCID 0000-0003-3782-767X
Kevin J SpringMedical Oncology, Ingham Institute for Applied Medical Research, School of Medicine, Western Sydney University and SWS Clinical School, UNSW, Sydney, NSW 2170, Australia.ORCID 0000-0003-0601-924X
Sandra HolmesPharmacy, School of Medicine, University of Tasmania, Hobart, TAS 7001, Australia.
Kiran AhujaSchool of Health Sciences, University of Tasmania, Newnham, TAS 7248, Australia.
Raj EriSchool of Health Sciences, University of Tasmania, Newnham, TAS 7248, Australia.
Ah Young ParkMarinova Pty Ltd., Cambridge, TAS 7170, Australia.
J Helen FittonMarinova Pty Ltd., Cambridge, TAS 7170, Australia.
University of Tasmania · AUUNSW Sydney · AU

Funding

Australian Department of Industry and Innovation (Innovations connections), grant number (RC49508). RC49508
6 · The paper itself

Abstract

Fucoidans are a class of fucose-rich sulfated polysaccharides derived from brown macroalgae that exert a range of biological activities in vitro and in vivo. To generate an unbiased assessment of pathways and processes affected by fucoidan, a placebo-controlled double-blind pilot study was performed in healthy volunteers. Blood samples were taken immediately before and 24 h after ingestion of a single dose of 1 g of

Indexed as

Administration, OralAdultAgedAnimalsAntineoplastic AgentsDouble-Blind MethodHealthy VolunteersHumansMaleMicroRNAsMiddle AgedPolysaccharidesSeaweedAntineoplastic AgentsfucoidanMicroRNAsPolysaccharidesclinicalfucoidanmicroRNA, anti-inflammatory, anti-cancer

Identifiers

PMID32121066
PMCPMC7143719
OpenAlexW3008994328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.