Evidence map›Paper›PMID 32121004›Full record

Trial reportNutrients2020

Microbiological and Immunological Markers in Milk and Infant Feces for Common Gastrointestinal Disorders: A Pilot Study.

Marina Aparicio, Claudio Alba, Proctocolitis Study Group Of Cam Public Health Area, Juan Miguel Rodríguez, Leonides Fernández

Abstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Frontiers in microbiology · 2024
    Article
  12. Article
  13. Article
  14. Administration ofFrontiers in microbiology · 2022
    Article
  15. Article
  16. Article
  17. Dynamics of the gut-liver axis in rats with varying fibrosis severity.International journal of biological sciences · 2022
    Article
  18. Review
  19. Article
  20. Administration ofFoods (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marina AparicioDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.
Claudio AlbaDepartment of Galenic Pharmacy and Food Technology, Complutense University of Madrid, 28040 Madrid, Spain.
Proctocolitis Study Group Of Cam Public Health AreaEAP Valle de la Oliva, Majadahonda, 28220 Madrid, Spain.
Juan Miguel RodríguezDepartment of Nutrition and Food Science, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1285-9686
Leonides FernándezDepartment of Galenic Pharmacy and Food Technology, Complutense University of Madrid, 28040 Madrid, Spain.ORCID 0000-0003-2380-0767

Funding

Spanish Ministry of Economy and Competitiveness AGL2016-75476-R
6 · The paper itself

Abstract

The objective of this pilot study was to assess the fecal microbiome and different immunological parameters in infant feces and maternal milk from mother-infant pairs in which the infants were suffering from different gastrointestinal disorders (colic, non-IgE-mediated cow milk protein allergy (CMPA), and proctocolitis). A cohort of 30 mother-infant pairs, in which the infants were diagnosed with these gastrointestinal disorders or included as healthy controls, were recruited. Bacterial composition of infant feces and breast milk was determined by metataxonomic sequencing. Immunological compounds were quantified using multiplexed immunoassays. A higher abundance of

Indexed as

BacteriaGastrointestinal DiseasesGastrointestinal MicrobiomeMilk, HumanAdultBiomarkersFecesFemaleHumansInfantInfant, NewbornMalePilot ProjectsBiomarkerscolichuman milkimmunologyinfant fecesintestinal diseasesmicrobiomenon-IgE-mediated allergypilot studyproctocolitis

Identifiers

PMID32121004
PMCPMC7146151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.