Evidence map›Paper›PMID 32120931›Full record

ArticleMolecules (Basel, Switzerland)2020

Total Synthesis of (-)-Anaferine: A Further Ramification in a Diversity-Oriented Approach.

Elisa Bonandi, Giada Tedesco, Dario Perdicchia, Daniele Passarella

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elisa BonandiUniversità degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy.
Giada TedescoUniversità degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy.
Dario PerdicchiaUniversità degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy.
Daniele PassarellaUniversità degli Studi di Milano, Via Golgi 19, 20133 Milano, Italy.ORCID 0000-0001-6180-9581

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The piperidine ring is a widespread motif in several natural bioactive alkaloids of both vegetal and marine origin. In the last years, a diversity-oriented synthetic (DOS) approach, aimed at the generation of a library of piperidine-based derivatives, was developed in our research group, employing commercially available 2-piperidine ethanol as a versatile precursor. Here, we report the exploration of another ramification of our DOS approach, that led us to the stereoselective total synthesis of (-)-anaferine, a bis-piperidine alkaloid present in

Indexed as

AlkaloidsEthanolPiperidinesPlant ExtractsStereoisomerismWithaniaAlkaloidsEthanolpiperidinePiperidinesPlant Extracts2-piperidine ethanolanaferinebis-piperidine alkaloidsdiversity-oriented synthesis

Identifiers

PMID32120931
PMCPMC7179133

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.