SynthesisInternational journal of environmental research and public health2020
The Impact of Shift-Work and Night Shift-Work on Thyroid: A Systematic Review.
Synthesis in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Association of Low Back Pain with Shift Work: A Meta-Analysis.International journal of environmental research and public health · 2023Pooled it
- Shift work is significantly and positively associated with dementia: A meta-analysis study.Frontiers in public health · 2023Pooled it
- Shift work is significantly and positively associated with possible gastro-esophageal reflux disease: A meta-analysis study.Frontiers in public health · 2022Pooled it
- Association of shift work and shift patterns with thyroid function: A NHANES-based cross-sectional study.Medicine · 2026Article
- Exposure to Radiation and Thyroid Cancer Risk Among Young Female Nurses: Longitudinal Analysis From the Korea Nurses' Health Study.JMIR cancer · 2025Article
- Investigating the relationship between shift work schedule and blood and metabolic parameters: a 10-years retrospective cohort study.Scientific reports · 2024Article
- Circulating white blood cell traits and prolonged night shifts: a cross-sectional study based on nurses in Guangxi.Scientific reports · 2024Article
- [Relationship between thyroid function changes with work-/night-shifts and history of thyroid pathology among health personnel].Anales del sistema sanitario de Navarra · 2024Article
- Rotating Night Shift Work, Sleep, and Thyroid Cancer Risk in the Nurses' Health Study 2.Cancers · 2023Article
- Circadian Rhythms in Cardiovascular Function: Implications for Cardiac Diseases and Therapeutic Opportunities.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Circadian clock disruption in autoimmune thyroiditis.European thyroid journal · 2023Article
- Predictors of Thyroid Disorders among Men and Women: A Population-Based Study.Medical journal of the Islamic Republic of Iran · 2023Article
- Association between shift work and the risk of hypothyroidism in adult male workers in Korea: a cohort study.Annals of occupational and environmental medicine · 2023Article
- Night Shift Work Is Associated with Reduced Rate of Humoral Response Following Vaccination for HBV.International journal of environmental research and public health · 2022Article
- Circadian Rhythm Effects on the Molecular Regulation of Physiological Systems.Comprehensive Physiology · 2021Review
- The Relationship Between Night Shift Work and the Risk of Abnormal Thyroid-Stimulating Hormone: A Hospital-Based Nine-Year Follow-up Retrospective Cohort Study in Taiwan.Safety and health at work · 2021Article
- Chronothyroidology: Chronobiological Aspects in Thyroid Function and Diseases.Life (Basel, Switzerland) · 2021Review
- Reinterpreting patterns of variation in human thyroid function: An evolutionary ecology perspective.Evolution, medicine, and public health · 2021Review
- Comparative Analysis of Metabolic and Endocrine Parameters in Night Shift versus Day Shift Workers: Insights from an Observational Study.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thyroid hormones are regulated by the pituitary thyroid stimulating hormone (TSH), whose secretion presents a circadian rhythmicity. Indeed, it is conceivable that shift- and night shift-work, affecting sleep-wake rhythms, may impact thyroid functionality. Therefore, the aim of the present review was to provide an overview on the association between shift- and night shift-work and thyroid hormonal changes and disease development. A systematic review of studies available in PubMed, Scopus, and ISI Web of Science databases was performed. A positive association between night shift-work and increased TSH concentrations was reported by most of the reviewed investigations. Inconclusive evidence was available on thyroid diseases. However, the limited number of studies, the noticeable heterogeneity in the shift-work scheduling, in terms of amount, duration, type of shift- or night shift-work, prevents easily integrating findings and extrapolating definite conclusions. Further investigation seems necessary to better define the relationship between shift schedules and different thyroid outcomes, and possible long-term implications of early functional changes. Overall, this may support the adoption of advanced risk assessment and management strategies aimed to achieve a safer workplace organization and a timely, responsible realization of all the benefits of a 24-h economy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.