ArticleInternational journal of environmental research and public health2020
Environmental Factors and Kawasaki Disease Onset in Emilia-Romagna, Italy.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Association between PMEuropean journal of pediatrics · 2026Article
- The effects of air pollutants and meteorological factors on the occurrence and regression of coronary artery lesions in Kawasaki disease: a study combining case-control and cohort studies.Italian journal of pediatrics · 2025Article
- Macrophage Activation Syndrome in Kawasaki Disease: Insights from a Systematic Literature Review on Diagnosis, Clinical Features, and Treatment.Children (Basel, Switzerland) · 2025Review
- Article
- The etiologies of Kawasaki disease.The Journal of clinical investigation · 2024Review
- Incidence and seasonality of Kawasaki disease in children in the Philippines, and its association with ambient air temperature.Frontiers in pediatrics · 2024Article
- Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease.Frontiers in microbiology · 2023Review
- Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease.Frontiers in immunology · 2023Article
- Prenatal and early life exposure to air pollution and the incidence of Kawasaki disease.Scientific reports · 2022Article
- Assessment of Pediatric Admissions for Kawasaki Disease or Infectious Disease During the COVID-19 State of Emergency in Japan.JAMA network open · 2021Article
- Is Short-Term Exposure to PMInternational journal of environmental research and public health · 2021Article
- Epidemiology of Kawasaki Disease in Europe.Frontiers in pediatrics · 2021Review
- Impact of climate change on rheumatic diseases: A scoping review.The journal of climate change and healthReview
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Kawasaki disease (KD)is an idiopathic acute febrile illness that primarily occurs in children <5 years of age and can lead to artery lesions if not promptly treated. Recent studies have shown possible correlations between KD onset and currents and air pollutants.The present study describes results on the correlation between environmental conditions, frequency, and variability ofKD onset in children under five years of age in Emilia-Romagna, a region of Northern Italy, over the period from 2000 to 2017. Since there are substantial climatic differences between the western-central (Emilia) and the eastern area (Romagna) of the region, the data for these areas are analyzed separately. The environmental factors considered are observed local surface daily temperature, daily precipitation, upper air wind regimes, and local air pollution. The results indicate that in Emilia-Romagna, KD onset occurs mainly during late autumn and early spring, which is in agreement with the literature. The frequency of KD onset in Emilia is significantly higher in months characterized by a high frequency of southerly flow, which is associated with milder than average night-time temperature, and in years with a prevailing south-westerly mean flow. These results are consistent with other studies, suggesting that certain wind conditions are more favorable for disease onset, which are possibly associated with one or more airborne agents.
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