ReviewSensors (Basel, Switzerland)2020
Advances in Sonothrombolysis Techniques Using Piezoelectric Transducers.
Review in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Sonothrombolysis as an adjunct to primary PCI in STEMI: a systematic review and meta-analysis of randomized trials.Journal of thrombosis and thrombolysis · 2026Pooled it
- Assessment of Cavitation From DEFINITY and DEFINITY RT.Ultrasound in medicine & biology · 2026Article
- Ultrasound-Mediated Thrombolysis: From Mechanistic Insights to Advanced Nanoplatforms and Clinical Translation.Advanced healthcare materials · 2026Review
- Study on Ultrasound Transducers With Alternating Current Poled Pb(MgIEEE transactions on ultrasonics · 2026Article
- Emerging Thrombolysis Technologies in Vascular Thrombosis.Journal of clinical medicine · 2025Review
- Synergistic sonothrombolysis based on coaxial confocal dual-frequency focused ultrasound and vortex beams.Ultrasonics sonochemistry · 2025Article
- Effect of Ultrasound on Thrombus debris during Sonothrombolysis in a Microfluidic device.Journal of thrombosis and thrombolysis · 2024Article
- Article
- Vortex-ultrasound for microbubble-mediated thrombolysis of retracted clots.Applied physics letters · 2023Article
- Miniaturized Stacked Transducer for Intravascular Sonothrombolysis With Internal-Illumination Photoacoustic Imaging Guidance and Clot Characterization.IEEE transactions on bio-medical engineering · 2023Article
- Estimating Thrombus Elasticity by Shear Wave Elastography to Evaluate Ultrasound Thrombolysis for Thrombus With Different Stiffness.IEEE transactions on bio-medical engineering · 2023Article
- Magnetic Nanoparticles Mediated Thrombolysis-A Review.IEEE open journal of nanotechnology · 2023Article
- Contrast enhanced sonothrombolysis using streptokinase loaded phase change nano-droplets for potential treatment of deep venous thrombosis.RSC advances · 2022Article
- Efficacy and safety of spot heating and ultrasound irradiation on in vitro and in vivo thrombolysis models.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Ultrasound-Guided Intravascular Sonothrombolysis With a Dual Mode Ultrasound Catheter: In Vitro Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2022Article
- Deep thrombosis characterization using photoacoustic imaging with intravascular light delivery.Biomedical engineering letters · 2022Article
- Enhanced thrombolysis by endovascular low-frequency ultrasound with bifunctional microbubbles in venous thrombosis:Frontiers in bioengineering and biotechnology · 2022Article
- Acoustics at the nanoscale (nanoacoustics): A comprehensive literature review.: Part II: Nanoacoustics for biomedical imaging and therapy.Sensors and actuators. A, Physical · 2021Article
- Dual-Frequency Intravascular Sonothrombolysis: An In Vitro Study.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2021Article
- In Vivo Porcine Aged Deep Vein Thrombosis Model for Testing Ultrasound-based Thrombolysis Techniques.Ultrasound in medicine & biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
One of the great advancements in the applications of piezoelectric materials is the application for therapeutic medical ultrasound for sonothrombolysis. Sonothrombolysis is a promising ultrasound based technique to treat blood clots compared to conventional thrombolytic treatments or mechanical thrombectomy. Recent clinical trials using transcranial Doppler ultrasound, microbubble mediated sonothrombolysis, and catheter directed sonothrombolysis have shown promise. However, these conventional sonothrombolysis techniques still pose clinical safety limitations, preventing their application for standard of care. Recent advances in sonothrombolysis techniques including targeted and drug loaded microbubbles, phase change nanodroplets, high intensity focused ultrasound, histotripsy, and improved intravascular transducers, address some of the limitations of conventional sonothrombolysis treatments. Here, we review the strengths and limitations of these latest pre-clincial advancements for sonothrombolysis and their potential to improve clinical blood clot treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.