ArticleViruses2020
The Segment Matters: Probable Reassortment of Tilapia Lake Virus (TiLV) Complicates Phylogenetic Analysis and Inference of Geographical Origin of New Isolate from Bangladesh.
Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 67 citations in OpenAlex.
- Phylogenetic and Proteomic Analyses of Segment 2 Sequence Reveals the Presence of Two Variants of a Divergent Amnoonvirus (Family:Microorganisms · 2026Article
- Exploring the Virome of Nile Tilapia (Pathogens (Basel, Switzerland) · 2025Article
- Investigation of Tilapia (Oreochromis niloticus) Mortality Events Targeting Tilapia Lake Virus Disease (TiLVD) in Bangladesh.Veterinary medicine and science · 2025Article
- Analyses and Insights into Genetic Reassortment and Natural Selection as Key Drivers ofViruses · 2024Article
- A multiplexed RT-PCR assay for nanopore whole genome sequencing of Tilapia lake virus (TiLV).Scientific reports · 2023Article
- Vitamin E supplementation in diet ameliorates growth of Nile tilapia by upgrading muscle health.Saudi journal of biological sciences · 2023Article
- Review
- Tilapia lake virus: A structured phylogenetic approach.Frontiers in genetics · 2023Article
- Impacts of climate change on fish hatchery productivity in Bangladesh: A critical review.Heliyon · 2022Review
- Persistent detection of Tilapia lake virus in wild tilapia and tinfoil barbs.Veterinary world · 2022Article
- Alterations in hematological parameters and the structure of peripheral erythrocytes in Nile tilapia (Oreochromis niloticus) exposed to profenofos.Environmental science and pollution research international · 2022Article
- Combining segments 9 and 10 in DNA and recombinant protein vaccines conferred superior protection against tilapia lake virus in hybrid red tilapia (Frontiers in immunology · 2022Article
- Application of fenitrothion onToxicology reports · 2022Article
- Tilapia Lake Virus was not detected in non-tilapine species within tilapia polyculture systems of Bangladesh.Journal of fish diseases · 2022Article
- Rapid genotyping of tilapia lake virus (TiLV) using Nanopore sequencing.Journal of fish diseases · 2021Article
- Face masks: protecting the wearer but neglecting the aquatic environment? - A perspective from Bangladesh.Environmental challenges (Amsterdam, Netherlands) · 2021Article
- Assessing the impacts of in-feed probiotic on the growth performance and health condition of pangasius (Aquaculture reports · 2021Article
- Presence of antibacterial substances, nitrofuran metabolites and other chemicals in farmed pangasius and tilapia in Bangladesh: Probabilistic health risk assessment.Toxicology reports · 2021Article
- Meta-Transcriptomic Identification of DivergentViruses · 2020Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Tilapia lake virus (TiLV), a negative sense RNA virus with a 10 segment genome, is an emerging threat to tilapia aquaculture worldwide, with outbreaks causing over 90% mortality reported on several continents since 2014. Following a severe tilapia mortality event in July 2017, we confirmed the presence of TiLV in Bangladesh and obtained the near-complete genome of this isolate, BD-2017. Phylogenetic analysis of the concatenated 10 segment coding regions placed BD-2017 in a clade with the two isolates from Thailand, separate from the Israeli and South American isolates. However, phylogenetic analysis of individual segments gave conflicting results, sometimes clustering BD-2017 with one of the Israeli isolates, and splitting pairs of isolates from the same region. By comparing patterns of topological difference among segments of quartets of isolates, we showed that TiLV likely has a history of reassortment. Segments 5 and 6, in particular, appear to have undergone a relatively recent reassortment event involving Ecuador isolate EC-2012 and Israel isolate Til-4-2011. The phylogeny of TiLV isolates therefore depends on the segment sequenced. Our findings illustrate the need to exercise caution when using phylogenetic analysis to infer geographic origin and track the movement of TiLV, and we recommend using whole genomes wherever possible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.