Evidence map›Paper›PMID 32120314›Full record

ArticleBiomaterials2020

Targeted melanoma radiotherapy using ultrasmall

Xiuli Zhang, Feng Chen, Melik Z Turker, Kai Ma, Pat Zanzonico, Fabio Gallazzi, Manankumar A Shah, Austin R Prater, Ulrich Wiesner, Michelle S Bradbury and 2 more

Open access · greenAbstract read
In one paragraph

Article in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Linking In Vivo Imaging to Therapeutic Outcome withInternational journal of molecular sciences · 2026
    Review
  4. Article
  5. Review
  6. Designing the Next Generation of Biomaterials through Nanoengineering.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
  7. Review
  8. Review
  9. Protein-functionalized and intrinsically radiolabeled [European journal of nuclear medicine and molecular imaging · 2025
    Article
  10. Article
  11. In Vitro Assessment ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Brachytherapy at the nanoscale with protein functionalized and intrinsically radiolabeled [European journal of nuclear medicine and molecular imaging · 2024
    Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. CeONanomaterials (Basel, Switzerland) · 2022
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Xiuli ZhangHarry S. Truman Veterans' Hospital, 800 Hospital Dr., Columbia, MO 65201, United States; Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States.
Feng ChenDepartment of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, United States.
Melik Z TurkerDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY 14853, United States.
Kai MaElucida Oncology, New York, NY 10016, United States.
Pat ZanzonicoDepartment of Medical Physics, Sloan Kettering Institute for Cancer Research, New York, NY 10065, United States.
Fabio GallazziDepartment of Chemistry and Research Core Facilities, University of Missouri, Columbia, MO 65211, United States.
Manankumar A ShahHarry S. Truman Veterans' Hospital, 800 Hospital Dr., Columbia, MO 65201, United States; Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States.
Austin R PraterHarry S. Truman Veterans' Hospital, 800 Hospital Dr., Columbia, MO 65201, United States; Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States.
Ulrich WiesnerDepartment of Materials Science and Engineering, Cornell University, Ithaca, NY 14853, United States.
Michelle S BradburyDepartment of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, United States; Molecular Pharmacology Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065, United States.
Michael R McDevittDepartment of Radiology, Sloan Kettering Institute for Cancer Research, New York, NY 10065, United States.
Thomas P QuinnHarry S. Truman Veterans' Hospital, 800 Hospital Dr., Columbia, MO 65201, United States; Department of Biochemistry, University of Missouri, Columbia, MO 65211, United States. Electronic address: Quinnt@missouri.edu.
Kettering University · USHarry S. Truman Memorial Veterans' Hospital · USCornell University · USUniversity of Missouri · USNew York Oncology Hematology · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Real-time Intraoperative Imaging of Cancer Biomarkers and Peripheral NervesU54CA199081 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI WIESNER, ULRICH · 2015 to 2019
$8.3M
Renally Excreted Multimodal Core-Shell Silica Nanoparticles as Tumor-Selective RaR01CA161280 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI BRADBURY, MICHELLE S, WIESNER, ULRICH · 2012 to 2016
$2.7M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA161280NCI NIH HHS U54 CA199081
6 · The paper itself

Abstract

Lutetium-177 (

Indexed as

MelanomaMelanoma, ExperimentalNanoparticlesalpha-MSHAnimalsCell Line, TumorHumansSilicon DioxideTissue Distributionalpha-MSHSilicon DioxideMelanomaRadionuclide therapyUltrasmall silica nanoparticleα-melanocyte stimulating hormone

Identifiers

PMID32120314
PMCPMC7171978
OpenAlexW3007635654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.