Evidence map›Paper›PMID 32120293›Full record

ArticleNeuroImage. Clinical2020

The role of limbic structures in financial abilities of mild cognitive impairment patients.

Silvia Benavides-Varela, Francesca Burgio, Luca Weis, Micaela Mitolo, Katie Palmer, Roberta Toffano, Giorgio Arcara, Antonino Vallesi, Dante Mantini, Francesca Meneghello and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05826548 (Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05826548 narecruitingnot on this mapstarted 2021, after this paper: background citation

Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program: FINAGE

TypeinterventionalSponsorIRCCS San Camillo, Venezia, ItalyRan2021 to 2025Enrolled140ConditionsParkinson Disease, Mild Cognitive Impairment, StrokeArmsTelerehabilitation group, Conventioanl treatment group
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Numerical activities of daily living: a short version.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  11. Predicting financial deficits from a standard neuropsychological assessment: preliminary evidence in mild cognitive impairment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Silvia Benavides-VarelaDepartment of Developmental Psychology and Socialisation, University of Padova, Padova, Italy; Department of General Psychology, University of Padova, Padova, Italy.
Francesca BurgioIRCCS San Camillo Hospital, Venice, Italy. Electronic address: francesca.burgio@ospedalesancamillo.net.
Luca WeisIRCCS San Camillo Hospital, Venice, Italy.
Micaela MitoloIRCCS Istituto delle Scienze Neurologiche di Bologna, Programma Neuroimmagini Funzionali e Molecolari, Bologna, Italy.
Katie PalmerDepartment of Geriatrics, Centro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy.
Roberta ToffanoIRCCS San Camillo Hospital, Venice, Italy.
Giorgio ArcaraIRCCS San Camillo Hospital, Venice, Italy.
Antonino VallesiIRCCS San Camillo Hospital, Venice, Italy; Department of Neuroscience and Padova Neuroscience Center, University of Padova, Padova, Italy.
Dante MantiniIRCCS San Camillo Hospital, Venice, Italy; Research Center for Neuroplasticity and Motor Control, KU Leuven, Leuven, Belgium.
Francesca MeneghelloIRCCS San Camillo Hospital, Venice, Italy.
Carlo SemenzaIRCCS San Camillo Hospital, Venice, Italy; Department of Neuroscience and Padova Neuroscience Center, University of Padova, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mild Cognitive Impairment (MCI) patients experience problems in financial abilities that affect everyday functioning. To date, the neural correlates of decline in this domain are unclear. This study aims at examining the correlation between the pattern of brain atrophy of MCI patients and performance on financial abilities. Forty-four MCI patients and thirty-seven healthy controls underwent structural magnetic resonance imaging, and assessment of financial abilitiesby means of the Numerical Activities of Daily Living Financial battery (NADL-F). As compared to healthy controls, MCI patients showed impaired performance in three out of the seven domains assessed by NADL-F: Item purchase, percentage, and financial concepts. The patients' performance in the NADL-F correlated with memory, language, visuo-spatial, and abstract reasoning composite scores. The analysis also revealed that volumetric differences in the limbic structures significantly correlated with financial abilities in MCI. Specifically, the patients' performance in the NADL-F was correlated with atrophy in the left medial and lateral amygdala and the right anterior thalamic radiation. These findings suggest that completing daily financial tasks involves sub-cortical regions in MCI and presumably also the motivational and emotional processes associated to them. Involvement of altered limbic structures in MCI patients suggests that impairment in financial abilities may be related to emotional and reflexive processing deficits.

Indexed as

Activities of Daily LivingMathematical ConceptsAgedAtrophyCognitive DysfunctionExecutive FunctionFemaleHumansLimbic SystemMagnetic Resonance ImagingMaleAlzheimer's diseaseEveryday functioningFinancial decisionsMCIPathological agingVBM

Identifiers

PMID32120293
PMCPMC7049652

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.