Evidence map›Paper›PMID 32120279›Full record

ArticleInternational journal of surgery case reports2020

Adrenocorticotropic hormone-producing pheochromocytoma: A case report.

Vadim Krylov, Ekaterina Dobreva, Sergey Kharnas, Nikolay Kuzntesov, Vladimir Nikolenko, Evegenia Marova, Vladimir Motalov, Vladimir Levkin, Yury Zharikov, Mikhail Sinelnikov

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Ectopic ACTH Syndrome Caused by Pheochromocytoma: A Case Report and Systematic Review.Endocrine, metabolic & immune disorders drug targets · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Vadim KrylovI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Ekaterina DobrevaEndocrinology Research Centre, Dmitriya Ulyanova Street, Moscow, 117036, Russian Federation.
Sergey KharnasI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Nikolay KuzntesovEndocrinology Research Centre, Dmitriya Ulyanova Street, Moscow, 117036, Russian Federation.
Vladimir NikolenkoI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Evegenia MarovaEndocrinology Research Centre, Dmitriya Ulyanova Street, Moscow, 117036, Russian Federation.
Vladimir MotalovI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Vladimir LevkinI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Yury ZharikovI.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Bolshaya Pirogovskaya St., 6/1, Moscow, 119146, Russian Federation.
Mikhail SinelnikovInstitute for Regenerative Medicine, Sechenov University, Trubetskaya, 8, 119431, Russian Federation. Electronic address: mikhail.y.sinelnikov@gmail.com.
Sechenov University · RUEndocrinology Research Center · RUCalifornia Institute for Regenerative Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCases of ectopic production of adrenocorticotropic hormone are considerably rare, but persistent in clinical practice. Extremely rare cases of ectopic production, such as via pheochromocytoma secretion, require special clinical attention and prior knowledge. It is important to understand the diagnostic algorithm for identifying ectopic sources of adrenocorticotropic hormone production. PRESENTATION OF CASE: In this clinical vignette we report a patient with a complex variety of clinical symptoms and no discernable cause for hypercriticism. Our clinical case outlines the diagnostic struggles, treatment challenges and surgical tactic for management of a rare ectopic ACTH producing pheochromocytoma. DISCUSSION: Highly variable clinical manifestations of ectopic ACTH producing pheochromocytoma, with typical signs of Cushing's syndrome and pheochromocytoma account for significant diagnostic difficulties and low incidence of verification of this pathology. Correction of symptoms and patient stabilization are of utmost importance throughout treatment.

conclusionACTH-dependent Cushing's syndrome, caused by a pheochromocytoma is extremely rare, but should be considered as a possible source for ACTH production. The diagnostic challenges of this condition can be met with confidence when a strict search protocol is conducted for detection of ACTH source.

Indexed as

ACTHACTH-ectopicCushing’s syndromePheochromocytoma

Identifiers

PMID32120279
PMCPMC7052437
OpenAlexW3004972170

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.