Evidence map›Paper›PMID 32119986›Full record

ArticleNeuroImage2020

Bagging improves reproducibility of functional parcellation of the human brain.

Aki Nikolaidis, Anibal Solon Heinsfeld, Ting Xu, Pierre Bellec, Joshua Vogelstein, Michael Milham

Abstract read
In one paragraph

Article in NeuroImage, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Consecutive-Contrastive Spherical U-Net: Enhancing Reliability of Individualized Functional Brain Parcellation for Short-Duration fMRI Scans.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2024
    Article
  5. Article
  6. Article
  7. Developmental deviation in delay discounting as a transdiagnostic indicator of risk for child psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2024
    Article
  8. Neural Systems Underlying the Implementation of Working Memory Removal Operations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Analyzing the Therapeutic Mechanism of Mongolian MedicineEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aki NikolaidisThe Child Mind Institute, 101 East 56th Street, New York, NY, 10022, USA. Electronic address: aki.nikolaidis@childmind.org.
Anibal Solon HeinsfeldUniversity of Texas at Austin, 110 Inner Campus Drive, Austin, TX 78705, USA.
Ting XuThe Child Mind Institute, 101 East 56th Street, New York, NY, 10022, USA.
Pierre BellecUniversity of Montreal, PO Box 6128 Downtown STN Montreal QC, H3C 3J7, Canada.
Joshua VogelsteinDepartment of Biomedical Engineering, Institute for Computational Medicine, Kavli Neuroscience Discovery Institute, Johns Hopkins University, 3400 N. Charles St Baltimore, MD, 21218, USA.
Michael MilhamThe Child Mind Institute, 101 East 56th Street, New York, NY, 10022, USA.

Funding

Project 5: ComputationalP50MH109429 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI STEPHANIE Ruggiano JONES · 2017 to 2026
$25.3M
Predicting Heterogeneous Neurodevelopmental Outcomes in School-age Children with Early Caregiving AdversitiesR01MH091864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MILHAM, MICHAEL PETER, TOTTENHAM, NIM · 2010 to 2022
$5.1M
Longitudinal Discovery of Brain Developmental TrajectoriesU01MH099059 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER · 2013 to 2017
$3.7M
Developmental Variations in Corticostriatal Thalamocortical Circuits and their Relationship to PsychopathologyR21MH118556 · NIMH · CHILD MIND INSTITUTE, INC. · PI NIKOLAIDIS, AKI · 2019 to 2020
$419k
NIMH NIH HHS R01 MH091864NIMH NIH HHS R21 MH118556NIMH NIH HHS U01 MH099059
6 · The paper itself

Abstract

Increasing the reproducibility of neuroimaging measurement addresses a central impediment to the advancement of human neuroscience and its clinical applications. Recent efforts demonstrating variance in functional brain organization within and between individuals shows a need for improving reproducibility of functional parcellations without long scan times. We apply bootstrap aggregation, or bagging, to the problem of improving reproducibility in functional parcellation. We use two large datasets to demonstrate that compared to a standard clustering framework, bagging improves the reproducibility and test-retest reliability of both cortical and subcortical functional parcellations across a range of sites, scanners, samples, scan lengths, clustering algorithms, and clustering parameters (e.g., number of clusters, spatial constraints). With as little as 6 ​min of scan time, bagging creates more reproducible group and individual level parcellations than standard approaches with twice as much data. This suggests that regardless of the specific parcellation strategy employed, bagging may be a key method for improving functional parcellation and bringing functional neuroimaging-based measurement closer to clinical impact.

Indexed as

BrainBrain MappingFunctional NeuroimagingHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingBaggingBasal gangliaBiomarkersBootstrapCluster ensemblesfMRIParcellationReliabilityReproducibilityStriatumSubcorticalThalamus

Identifiers

PMID32119986
PMCPMC7302537

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.