Evidence map›Paper›PMID 32119734›Full record

ArticleThe American journal of clinical nutrition2020

Weight gain during pregnancy and the risk of severe maternal morbidity by prepregnancy BMI.

Stephanie A Leonard, Barbara Abrams, Elliott K Main, Deirdre J Lyell, Suzan L Carmichael

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephanie A LeonardDivision of Neonatal and Developmental Medicine, Stanford University, Stanford, CA, USA.
Barbara AbramsDivision of Epidemiology, University of California, Berkeley, CA, USA.
Elliott K MainDivision of Maternal-Fetal Medicine and Obstetrics, Stanford University, Stanford, CA, USA.
Deirdre J LyellDivision of Maternal-Fetal Medicine and Obstetrics, Stanford University, Stanford, CA, USA.
Suzan L CarmichaelDivision of Neonatal and Developmental Medicine, Stanford University, Stanford, CA, USA.
Stanford University · USUniversity of California, Berkeley · US

Funding

Severe Maternal Morbidity: An Investigation of Racial-Ethnic Disparities, Social Disadvantage & Maternal WeightR01NR017020 · NINR · STANFORD UNIVERSITY · PI SUZAN L CARMICHAEL · 2018 to 2026
$5.2M
Understanding Severe Maternal Morbidity: Predictors, Trends, and DisparitiesF32HD091945 · NICHD · STANFORD UNIVERSITY · PI LEONARD, STEPHANIE A. · 2017 to 2018
$115k
NICHD NIH HHS F32 HD091945NINR NIH HHS R01 NR017020
6 · The paper itself

Abstract

backgroundHigh and low prepregnancy BMI are risk factors for severe maternal morbidity (SMM), but the contribution of gestational weight gain (GWG) is not well understood.

objectivesWe evaluated associations between GWG and SMM by prepregnancy BMI group.

methodsWe analyzed administrative records from 2,483,684 Californian births (2007-2012), utilizing z score charts to standardize GWG for gestational duration. We fit the z scores nonlinearly and categorized GWG as above, within, or below the Institute of Medicine (IOM) recommendations after predicting equivalent GWG at term from the z score charts. SMM was defined using a validated index. Associations were estimated using multivariable logistic regression models.

resultsWe found generally shallow U-shaped relations between GWG z score and SMM in all BMI groups, except class 3 obesity (≥40 kg/m2), for which risk was lowest with weight loss. The weight gain amount associated with the lowest risk of SMM was within the IOM recommendations for underweight and class 2 obesity, but above the IOM recommendations for normal weight, overweight, and class 1 obesity. The adjusted risk ratios (RRs) and 95% CIs for GWG below the IOM recommendations, compared with GWG within the recommendations, were the following for underweight, normal weight, overweight, class 1 obesity, class 2 obesity, and class 3 obesity: 1.13 (0.99, 1.29), 1.09 (1.04, 1.14), 1.10 (1.01, 1.19), 1.07 (0.95, 1.21), 1.03 (0.88, 1.22), and 0.89 (0.73, 1.08), respectively. For GWG above the recommendations, the corresponding RRs and 95% CIs were 0.99 (0.84, 1.15), 1.04 (0.99, 1.08), 0.98 (0.92, 1.04), 1.03 (0.95, 1.13), 1.07 (0.94, 1.23), and 1.08 (0.91, 1.30), respectively.

conclusionsHigh and low GWG may be modestly associated with increased risk of SMM across BMI groups, except in women with class 3 obesity, for whom low weight gain and weight loss may be associated with decreased risk of SMM.

Indexed as

Weight GainAdultBody Mass IndexFemaleHumansMorbidityOverweightPregnancyPregnancy ComplicationsPregnancy OutcomeYoung Adultmaternal healthmaternal mortalityobesitypopulation healthpregnancypregnancy complicationsweight gainweight loss

Identifiers

PMID32119734
PMCPMC7138679
OpenAlexW3009556507

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.