Evidence map›Paper›PMID 32119067›Full record

ArticleBioinformatics (Oxford, England)2020

CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation.

Emmanuel L P Dumont, Benjamin Tycko, Catherine Do

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emmanuel L P DumontHackensack-Meridian Health Center for Discovery and Innovation, Nutley, NJ 07110, USA.
Benjamin TyckoHackensack-Meridian Health Center for Discovery and Innovation, Nutley, NJ 07110, USA.
Catherine DoHackensack-Meridian Health Center for Discovery and Innovation, Nutley, NJ 07110, USA.

Funding

DNA Elements Underlying Celiac and Crohn's SusceptibilityR21AI133140 · NIAID · HACKENSACK UNIVERSITY MEDICAL CENTER · PI TYCKO, BENJAMIN · 2017 to 2018
$489k
NIAID NIH HHS R21 AI133140
6 · The paper itself

Abstract

summaryMethods for quantifying the imbalance in CpG methylation between alleles genome-wide have been described but their algorithmic time complexity is quadratic and their practical use requires painstaking attention to infrastructure choice, implementation and execution. To solve this problem, we developed CloudASM, a scalable, ultra-efficient, turn-key, portable pipeline on Google Cloud Platform (GCP) that uses a novel pipeline manager and GCP's serverless enterprise data warehouse. AVAILABILITY AND IMPLEMENTATION: CloudASM is freely available in the GitHub repository https://github.com/TyckoLab/CloudASM and a sample dataset and its results are also freely available at https://console.cloud.google.com/storage/browser/cloudasm. CONTACT: emmanuel.dumont@hmh-cdi.org.

Indexed as

DNA MethylationSoftwareAllelesCloud Computing

Identifiers

PMID32119067
PMCPMC7267820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.