Evidence map›Paper›PMID 32118758›Full record

ArticleMedicine2020

Application of computed tomography, positron emission tomography-computed tomography, magnetic resonance imaging, endobronchial ultrasound, and mediastinoscopy in the diagnosis of mediastinal lymph node staging of non-small-cell lung cancer: A protocol for a systematic review.

Longguo Zhang, Fanqi Wu, Rui Zhu, Di Wu, Yao Ding, Zhongmei Zhang, Ya Gao, Yixin Wan, Mediastinal N Staging Assessment Working Group

Abstract read
In one paragraph

Article in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Longguo ZhangThe Second Clinical Medical School of Lanzhou University.
Fanqi WuDepartment of Respiratory, Lanzhou University Second Hospital.
Rui ZhuThe Second Clinical Medical School of Lanzhou University.
Di WuThe Second Clinical Medical School of Lanzhou University.
Yao DingThe First Clinical Medical College.
Zhongmei ZhangThe Second Clinical Medical School of Lanzhou University.
Ya GaoEvidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, China.
Yixin WanDepartment of Respiratory, Lanzhou University Second Hospital.
Mediastinal N Staging Assessment Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRuling out distant metastases, non-small cell lung cancer (NSCLC)treatment depends on the results of mediastinal node staging (N staging). Several diagnostic methods play central roles in mediastinal N staging. This study is intended to evaluate the existing diagnostic methods and report quality, and to search for the best method for staging mediastinal lymph nodes.

methodsWe searched PubMed, Embase, and the Cochrane Library to identify relevant studies, including randomized controlled trials and retrospective studies. These studies report the application of computed tomography, positron emission tomography-computed tomography, magnetic resonance imaging, endobronchial ultrasound, and mediastinoscopy in the diagnosis of mediastinal lymph node staging of NSCLC. The quality of the literature was assessed using the Quality Assessment of Diagnostic Accuracy Study 2. The true positive, false positive, true negative, and false negative of each study was extracted. The corresponding sensitivity, specificity, and other indicators were calculated and the Summary Receiver Operating curve was established. Then, head-to-head and indirect comparison meta-analyses will be conducted.

resultsThe results of this study will be published in a peer-reviewed journal.

conclusionThis study will provide basis for mediastinal lymph node staging of non-small cell lung cancer. PROSPERO REGISTRATION NUMBER: CRD42019145667.

Indexed as

AgedCarcinoma, Non-Small-Cell LungClinical ProtocolsDiagnostic ImagingEndoscopyFemaleHumansLymph NodesMagnetic Resonance ImagingMaleMediastinoscopyMiddle AgedNeoplasm StagingPositron Emission Tomography Computed TomographyTomography, X-Ray ComputedUltrasonography

Identifiers

PMID32118758
PMCPMC7478550

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.