Evidence map›Paper›PMID 32118120›Full record

ArticleWellcome open research2019

Knowledge gaps and research priorities in tuberculous meningitis.

James A Seddon, Robert Wilkinson, Reinout van Crevel, Anthony Figaji, Guy E Thwaites, Tuberculous Meningitis International Research Consortium

Abstract read
In one paragraph

Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Clinical standards for drug-susceptible TB in children and adolescents.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  8. A qualitative study of factors resulting in care delays for adults with meningitis in Zambia.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James A SeddonInfectious Diseases, Imperial College London, London, W2 1PG, UK.ORCID https://orcid.org/0000-0002-2296-2302
Robert WilkinsonInfectious Diseases, Imperial College London, London, W2 1PG, UK.ORCID https://orcid.org/0000-0002-2753-1800
Reinout van CrevelDepartment of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-6233-6410
Anthony FigajiNeuroscience Institute, Division of Neurosurgery, University of Cape Town, Cape Town, South Africa.ORCID https://orcid.org/0000-0002-3357-6490
Guy E ThwaitesCentre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID https://orcid.org/0000-0002-2858-2087
Tuberculous Meningitis International Research Consortium

Funding

Medical Research Council MR/R007942/1Wellcome Trust 110179/Z/15/ZWellcome Trust FC001218
6 · The paper itself

Abstract

Tuberculous meningitis (TBM) is the most severe and disabling form of tuberculosis (TB), accounting for around 1-5% of the global TB caseload, with mortality of approximately 20% in children and up to 60% in persons co-infected with human immunodeficiency virus even in those treated. Relatively few centres of excellence in TBM research exist and the field would therefore benefit from greater co-ordination, advocacy, collaboration and early data sharing. To this end, in 2009, 2015 and 2019 we convened the TBM International Research Consortium, bringing together approximately 50 researchers from five continents. The most recent meeting took place on 1

Indexed as

Care CascadeCritical CareDiagnosisEpidemiologyResearch PrioritiesTreatmentTuberculosisTuberculous Meningitis

Identifiers

PMID32118120
PMCPMC7014926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.