Evidence map›Paper›PMID 32118040›Full record

ArticleFrontiers in molecular biosciences2020

3D Co-culture of hiPSC-Derived Cardiomyocytes With Cardiac Fibroblasts Improves Tissue-Like Features of Cardiac Spheroids.

Philippe Beauchamp, Christopher B Jackson, Lijo Cherian Ozhathil, Irina Agarkova, Cristi L Galindo, Douglas B Sawyer, Thomas M Suter, Christian Zuppinger

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 2 pooled it
22.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 2 syntheses or guidelines pooled it, 186 citations in OpenAlex.

  1. Pooled it
  2. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
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  16. Beyond monolayers: a comparative analysis of 2D cell cultures and 3DFrontiers in bioengineering and biotechnology · 2026
    Review
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60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Philippe BeauchampCardiology Department, DBMR MEM C812, Bern University Hospital, Bern, Switzerland.
Christopher B JacksonStem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Lijo Cherian OzhathilDepartment of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Irina AgarkovaInSphero AG, Schlieren, Switzerland.
Cristi L GalindoDivision of Cardiovascular Medicine, Vanderbilt University Medical School, Nashville, TN, United States.
Douglas B SawyerDepartment of Cardiac Services, Maine Medical Center, Scarborough, ME, United States.
Thomas M SuterCardiology Department, DBMR MEM C812, Bern University Hospital, Bern, Switzerland.
Christian ZuppingerCardiology Department, DBMR MEM C812, Bern University Hospital, Bern, Switzerland.
University Hospital of Bern · CHInspire · CHMaine Medical Center · USUniversity of Copenhagen · DKUniversity of Helsinki · FIVanderbilt University · US

Funding

Vanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3M
NIDDK NIH HHS P30 DK020593
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

3D-culturecardiomyocyteco-culturefibroblastinduced pluripotent stem cellsmicrotissuemyofibroblastscaffold-free

Identifiers

PMID32118040
PMCPMC7033479
OpenAlexW3006530715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.