Evidence map›Paper›PMID 32118008›Full record

ArticleFrontiers in medicine2020

Effect of Calcitriol on the Renal Microvasculature Differentiation Disturbances Induced by AT

Amanda L Deluque, Lucas F de Almeida, Heloísa D C Francescato, Cleonice G A da Silva, Roberto S Costa, José Antunes-Rodrigues, Terezila M Coimbra

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Potential role of hypovitaminosis D and vitamin D supplementation during COVID-19 pandemic.QJM : monthly journal of the Association of Physicians · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Amanda L DeluqueLaboratory of Renal Physiology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Lucas F de AlmeidaLaboratory of Renal Physiology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Heloísa D C FrancescatoLaboratory of Renal Physiology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Cleonice G A da SilvaLaboratory of Renal Physiology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Roberto S CostaLaboratory of Renal Pathology, Division of Nephrology, Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
José Antunes-RodriguesLaboratory of Neuroendocrinology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Terezila M CoimbraLaboratory of Renal Physiology, Department of Physiology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations in the renal vasculature during fetal programming can cause disturbances in renal structure and function that persist into adulthood. Calcitriol can affect cellular differentiation and proliferation, and promote endothelial cell maintenance, each of which is a key event in nephrogenesis. Calcitriol is a negative endocrine regulator of the renin gene. Rats exposed to renin-angiotensin system (RAS) antagonists during lactation have been shown to develop renal disorders, which demonstrated that the RAS may play an important role in mammalian kidney development. We evaluated the effects of calcitriol administration on losartan [angiotensin II receptor antagonist (ANGII), AT

Indexed as

calcitriolcell differentiationkidney developmentrenal microvasculaturerenin-angiotensin system

Identifiers

PMID32118008
PMCPMC7016013
OpenAlexW3005401427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.