Evidence map›Paper›PMID 32118007›Full record

ReviewFrontiers in medicine2020

Acute Kidney Injury in Pregnancies Complicated With Preeclampsia or HELLP Syndrome.

Jamie Szczepanski, Ashley Griffin, Sarah Novotny, Kedra Wallace

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jamie SzczepanskiDepartment of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS, United States.
Ashley GriffinProgram in Neuroscience, University of Mississippi Medical Center, Jackson, MS, United States.
Sarah NovotnyDepartment of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS, United States.
Kedra WallaceDepartment of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson, MS, United States.

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
Hypertension and Cardiorenal Research Training ProgramT32HL105324 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Joey P. Granger · 2010 to 2026
$7.8M
Hypertension and Neuroinflammation during Pregnancy – The Impact on Maternal Behavior and Offspring NeurodevelopmentR01MH116027 · NIMH · UNIVERSITY OF MISSISSIPPI MED CTR · PI WALLACE, KEDRA L. · 2018 to 2019
$640k
NHLBI NIH HHS T32 HL105324NIGMS NIH HHS P20 GM121334NIMH NIH HHS R01 MH116027
6 · The paper itself

Abstract

Acute kidney injury that occurs during pregnancy or in the post-partum period (PR-AKI) is a serious obstetric complication with risk of significant associated maternal and fetal morbidity and mortality. Recent data indicates that the incidence of PR-AKI is increasing, although accurate calculation is limited by the lack of a uniform diagnostic criteria that is validated in pregnancy. Hypertensive and thrombotic microangiopathic disorders of pregnancy have been identified as major contributors to the burden of PR-AKI. As is now accepted regarding preeclampsia, HELLP syndrome and atypical hemolytic uremic syndrome, it is believed that PR-AKI may have long-term renal, cardiovascular and neurocognitive consequences that persist beyond the post-partum period. Further research regarding PR-AKI could be advanced by the development of a pregnancy-specific validated definition and classification system; and the establishment of refined animal models that would allow researchers to further elucidate the mechanisms and sequelae of the disorder.

Indexed as

acute kidney injury (AKI)chronic kidney disease (CKD)hemolysis elevated liver enzymes low platelet count (HELLP)preeclampsiarenal injury

Identifiers

PMID32118007
PMCPMC7020199

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.