Evidence map›Paper›PMID 32117929›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Getting CD19 Into Shape: Expression of Natively Folded "Difficult-to- Express" CD19 for Staining and Stimulation of CAR-T Cells.

Elisabeth Lobner, Anna Wachernig, Venugopal Gudipati, Patrick Mayrhofer, Benjamin Salzer, Manfred Lehner, Johannes B Huppa, Renate Kunert

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Splicing by Overlap Extension PCR for the Production of Fusion Proteins.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Label-free methods for opticalPhysical chemistry chemical physics : PCCP · 2021
    Review
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisabeth LobnerDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Anna WachernigDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Venugopal GudipatiInstitute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Patrick MayrhoferDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.
Benjamin SalzerSt. Anna Children's Cancer Research Institute, Vienna, Austria.
Manfred LehnerSt. Anna Children's Cancer Research Institute, Vienna, Austria.
Johannes B HuppaInstitute for Hygiene and Applied Immunology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, Austria.
Renate KunertDepartment of Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.

Funding

Austrian Science Fund FWF W 1224
6 · The paper itself

Abstract

The transmembrane protein CD19 is exclusively expressed on normal and malignant B cells and therefore constitutes the target of approved CAR-T cell-based cancer immunotherapies. Current efforts to assess CAR-T cell functionality in a quantitative fashion both

Indexed as

BACCAR-T cellCD19chemical chaperonesdifficult-to-express proteinT cell activationTIRF

Identifiers

PMID32117929
PMCPMC7020774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.