Evidence map›Paper›PMID 32117884›Full record

ArticleFrontiers in chemistry2020

Surface Dependent Dual Recognition of a G-quadruplex DNA With Neomycin-Intercalator Conjugates.

Nihar Ranjan, Katrine F Andreasen, Yashaswina Arora, Liang Xue, Dev P Arya

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nihar RanjanLaboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States.
Katrine F AndreasenLaboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States.
Yashaswina AroraDepartment of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Raebareli, India.
Liang XueLaboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States.
Dev P AryaLaboratory for Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC, United States.
Clemson University · USNational Institute of Pharmaceutical Education and Research · IN

Funding

Aminoglycosides with reduced ototoxicityR42AI126874 · NIAID · NUBAD, LLC · PI ARYA, DEV PRIYA · 2021 to 2024
$3.0M
A Rapid assay for RNA targeted drugs: Instrumentation SupplementR42GM097917 · NIGMS · NUBAD, LLC · PI ARYA, DEV PRIYA · 2014 to 2015
$1.4M
Aminoglycosides with reduced ototoxicityR41AI126874 · NIAID · NUBAD, LLC · PI ARYA, DEV PRIYA · 2016 to 2017
$600k
A novel assay for RNA targeted drugsR41GM097917 · NIGMS · NUBAD, LLC · PI ARYA, DEV PRIYA · 2011 to 2011
$286k
NIAID NIH HHS R41 AI126874NIAID NIH HHS R42 AI126874NIGMS NIH HHS R41 GM097917NIGMS NIH HHS R42 GM097917
6 · The paper itself

Abstract

G-quadruplexes have been characterized as structures of vital importance in the cellular functioning of several life forms. They have subsequently been established to serve as a therapeutic target of several diseases including cancer, HIV, tuberculosis and malaria. In this paper, we report the binding of aminosugar-intercalator conjugates with a well-studied anti-parallel G-quadruplex derived from

Indexed as

DNAFIDG-quadruplexneomycinOxytricha Nova

Identifiers

PMID32117884
PMCPMC7028757
OpenAlexW3006665342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.