Evidence map›Paper›PMID 32117802›Full record

ArticleFrontiers in cellular and infection microbiology2020

What Are the Functions of Chitin Deacetylases in

Isabelle Mouyna, Sarah Dellière, Anne Beauvais, Fabrice Gravelat, Brendan Snarr, Mélanie Lehoux, Caitlin Zacharias, Yan Sun, Steven de Jesus Carrion, Eric Pearlman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  13. Diverse signatures of convergent evolution in cacti-associated yeasts.bioRxiv : the preprint server for biology · 2023
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  14. Review
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  16. Immunity to pathogenic fungi in the eye.Seminars in immunology · 2023
    Review
  17. Solid-state NMR molecular snapshots ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Isabelle MouynaAspergillus Unit, Pasteur Institut, Paris, France.
Sarah DellièreInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Anne BeauvaisAspergillus Unit, Pasteur Institut, Paris, France.
Fabrice GravelatInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Brendan SnarrInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Mélanie LehouxInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Caitlin ZachariasInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Yan SunDepartment of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, United States.
Steven de Jesus CarrionDepartment of Ophthalmology and Visual Sciences, Case Western Reserve University, Cleveland, OH, United States.
Eric PearlmanDepartment of Ophthalmology, University of California, Irvine, Irvine, CA, United States.
Donald C SheppardInfectious Diseases in Global Health Program, Centre for Translational Biology, McGill University Health Centre, Montréal, QC, Canada.
Jean-Paul LatgéAspergillus Unit, Pasteur Institut, Paris, France.
Institut Pasteur · FRMcGill University · CAMcGill University Health Centre · CACase Western Reserve University · USIrvine University · US

Funding

Pathogenesis of Fungal KeratitisR01EY018612 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI PEARLMAN, ERIC · 2008 to 2022
$6.9M
NEI NIH HHS R01 EY018612
6 · The paper itself

Abstract

Deacetylation of chitin by chitin deacetylases (Cda) results in the formation of chitosan. Chitosan, a polymer of β1,4 linked glucosamine, plays multiple roles in the function of the fungal cell wall, including virulence and evasion of host immune responses. In this study, the roles of chitosan and putative

Indexed as

Aspergillus fumigatusCell WallChitinSpores, FungalVirulenceChitinAspergillus fumigatuscell wallchitinchitin deacetylasechitosanconidiafilamentous fungi

Identifiers

PMID32117802
PMCPMC7016196
OpenAlexW3005406464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.