Evidence map›Paper›PMID 32117536›Full record

ArticleClinics in orthopedic surgery2020

Lupus and Perioperative Complications in Elective Primary Total Hip or Knee Arthroplasty.

Keith T Aziz, Matthew J Best, Richard L Skolasky, Karthik E Ponnusamy, Robert S Sterling, Harpal S Khanuja

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Clinics in orthopedic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Keith T AzizDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Matthew J BestDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Richard L SkolaskyDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Karthik E PonnusamyDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Robert S SterlingDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Harpal S KhanujaDepartment of Orthopaedic Surgery, The Johns Hopkins Hospital, Baltimore, MD, USA.
Johns Hopkins Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of patients with systemic lupus erythematosus (herein, lupus) undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA) is increasing. There is disagreement about the effect of lupus on perioperative complication rates. We hypothesized that lupus would be associated with higher complication rates in patients who undergo elective primary THA or TKA.

methodsRecords of more than 6.2 million patients from the National Inpatient Sample who underwent elective primary THA or TKA from 2000 to 2009 were reviewed. Patients with lupus (n = 38,644) were compared with those without lupus (n = 6,173,826). Major complications were death, pulmonary embolism, myocardial infarction, stroke, pneumonia, and acute renal failure. Minor complications were wound infection, seroma, deep vein thrombosis, hip dislocation, wound dehiscence, and hematoma. Patient age, sex, duration of hospital stay, and number of Elixhauser comorbidities were assessed for both groups. Multivariate logistic regression models using comorbidities, age, and sex as covariates were used to assess the association of lupus with major and minor perioperative complications. The alpha level was set to 0.001.

resultsAmong patients who underwent THA, those with lupus were younger (mean age, 56 vs. 65 years), were more likely to be women (87% vs. 56%), had longer hospital stays (mean, 4.0 vs. 3.8 days), and had more comorbidities (mean, 2.5 vs. 1.4) than those without lupus (all

conclusionsLupus is an independent risk factor for major and minor perioperative complications in elective primary THA but not TKA.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeAgedElective Surgical ProceduresFemaleHumansLupus Erythematosus, SystemicMaleMiddle AgedPerioperative PeriodPostoperative ComplicationsArthroplasty, Total hipArthroplasty, Total kneeComplicationsPerioperativeSystemic lupus erythematosus

Identifiers

PMID32117536
PMCPMC7031438
OpenAlexW3007106532

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.