Evidence map›Paper›PMID 32117314›Full record

ArticleFrontiers in immunology2020

CD1b Tetramers Broadly Detect T Cells That Correlate With Mycobacterial Exposure but Not Tuberculosis Disease State.

Kattya Lopez, Sarah K Iwany, Sara Suliman, Josephine F Reijneveld, Tonatiuh A Ocampo, Judith Jimenez, Roger Calderon, Leonid Lecca, Megan B Murray, D Branch Moody and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Metabolic control of innate-like T cells.Nature reviews. Immunology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. CD1 displays its own negative regulators.Current opinion in immunology · 2023
    Review
  9. Review
  10. Role of MHC class I pathways inFrontiers in cellular and infection microbiology · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. International journal of molecular sciences · 2021
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Kattya LopezSocios En Salud, Lima, Peru.
Sarah K IwanyDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Sara SulimanDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Josephine F ReijneveldDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Tonatiuh A OcampoDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Judith JimenezSocios En Salud, Lima, Peru.
Roger CalderonSocios En Salud, Lima, Peru.
Leonid LeccaSocios En Salud, Lima, Peru.
Megan B MurrayDivision of Global Health Equity, Department of Global Health and Social Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
D Branch MoodyDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Ildiko Van RhijnDivision of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, United States.
Brigham and Women's Hospital · USEsSALUD · PEHarvard University · US

Funding

Metabolomics Core U19AI111224 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MURRAY, MEGAN, MURRAY, MEGAN B · 2015 to 2021
$20.4M
T cell response to CDI-restricted lipids in tuberculosisR01AI049313 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2001 to 2025
$10.6M
NIAID NIH HHS R01 AI049313NIAID NIH HHS U19 AI111224
6 · The paper itself

Abstract

The non-polymorphic nature of CD1 proteins creates a situation in which T cells with invariant T cell receptors (TCRs), like CD1d-specific NKT cells, are present in all humans. CD1b is an abundant protein on human dendritic cells that presents

Indexed as

AdultAntigens, CD1FemaleGlycolipidsHumansLeukocyte Common AntigensMaleMiddle AgedMycobacterium tuberculosisMycolic AcidsReceptors, Antigen, T-CellT-LymphocytesTuberculosisAntigens, CD1CD1b antigenglucose mycolateGlycolipidsLeukocyte Common AntigensMycolic AcidsReceptors, Antigen, T-CellCD1bglycolipidsmycobacteriaT cell receptortetramertuberculosis

Identifiers

PMID32117314
PMCPMC7033476
OpenAlexW3005670677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.