Evidence map›Paper›PMID 32117241›Full record

ArticleFrontiers in immunology2020

Magnolol Attenuates Cisplatin-Induced Muscle Wasting by M2c Macrophage Activation.

Chanju Lee, Hyunju Jeong, Hyunji Lee, Minwoo Hong, Seon-Young Park, Hyunsu Bae

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  5. Mediators of inflammation · 2025
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  8. Regulatory macrophages in solid organ xenotransplantation.Korean journal of transplantation · 2023
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  11. Article
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  18. Macrophages augment the skeletal muscle proinflammatory response through TNFα following LPS-induced acute lung injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chanju LeeDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Hyunju JeongDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Hyunji LeeDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Minwoo HongDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Seon-Young ParkDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Hyunsu BaeDepartment of Physiology, College of Korean Medicine, Kyung Hee University, Seoul, South Korea.
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer chemotherapy induces sarcopenia, which is a rapid loss of muscle mass that directly restricts daily activities and leads to poor quality of life and increased mortality. Although hormone-related therapies have been used to improve appetite and nutritional status, current treatments are considered palliative. Thus, the protection of skeletal muscle loss without adverse effects is essential to allow the maintenance of chemotherapy in cancer patients. Magnolol from

Indexed as

AnimalsAntineoplastic AgentsBiphenyl CompoundsCarcinoma, Lewis LungCisplatinLignansMacrophage ActivationMacrophagesMaleMiceMice, Inbred C57BLMuscular AtrophyAntineoplastic AgentsBiphenyl CompoundsCisplatinLignansmagnololcisplatinM2c macrophagesmagnololmuscle atrophysarcopenia

Identifiers

PMID32117241
PMCPMC7018987
OpenAlexW3004923500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.