Evidence map›Paper›PMID 32117225›Full record

ReviewFrontiers in immunology2020

Novel Insights Into Immune Systems of Bats.

Arinjay Banerjee, Michelle L Baker, Kirsten Kulcsar, Vikram Misra, Raina Plowright, Karen Mossman

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 1 synthesis or guideline pooled it, 367 citations in OpenAlex.

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113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Arinjay BanerjeeDepartment of Pathology and Molecular Medicine, Michael DeGroote Institute for Infectious Disease Research, McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.
Michelle L BakerHealth and Biosecurity Business Unit, Australian Animal Health Laboratory, CSIRO, Geelong, VIC, Australia.
Kirsten KulcsarDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, United States.
Vikram MisraDepartment of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.
Raina PlowrightDepartment of Microbiology and Immunology, Montana State University, Bozeman, MT, United States.
Karen MossmanDepartment of Pathology and Molecular Medicine, Michael DeGroote Institute for Infectious Disease Research, McMaster Immunology Research Centre, McMaster University, Hamilton, ON, Canada.
Commonwealth Scientific and Industrial Research Organisation · AUMcMaster University · CAMcMaster University Medical Centre · CAMontana State University · USUniversity of Maryland, Baltimore · USUniversity of Saskatchewan · CA

Funding

CIHR
6 · The paper itself

Abstract

In recent years, viruses similar to those that cause serious disease in humans and other mammals have been detected in apparently healthy bats. These include filoviruses, paramyxoviruses, and coronaviruses that cause severe diseases such as Ebola virus disease, Marburg haemorrhagic fever and severe acute respiratory syndrome (SARS) in humans. The evolution of flight in bats seem to have selected for a unique set of antiviral immune responses that control virus propagation, while limiting self-damaging inflammatory responses. Here, we summarize our current understanding of antiviral immune responses in bats and discuss their ability to co-exist with emerging viruses that cause serious disease in other mammals. We highlight how this knowledge may help us to predict viral spillovers into new hosts and discuss future directions for the field.

Indexed as

Adaptive ImmunityAnimalsChiropteraDisease ReservoirsDNA VirusesEvolution, MolecularHost AdaptationImmune SystemImmunity, InnateInterferonsRNA VirusesViral ZoonosesInterferonsantiviralbats (Chiroptera)emerging virusesinnate and adaptive immune responseinterferonvirus

Identifiers

PMID32117225
PMCPMC7025585
OpenAlexW3002458416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.