Evidence map›Paper›PMID 32117207›Full record

ArticleFrontiers in immunology2019

Crucial Involvement of IL-6 in Thrombus Resolution in Mice via Macrophage Recruitment and the Induction of Proteolytic Enzymes.

Mizuho Nosaka, Yuko Ishida, Akihiko Kimura, Yumi Kuninaka, Akira Taruya, Mitsunori Ozaki, Atushi Tanaka, Naofumi Mukaida, Toshikazu Kondo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  8. NanoSHP099-Targeted SHP2 Inhibition Boosts Ly6CAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Immune cell-mediated venous thrombus resolution.Research and practice in thrombosis and haemostasis · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. The role of monocytes in thrombotic diseases: a review.Frontiers in cardiovascular medicine · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mizuho NosakaDepartment of Forensic Medicine, Wakayama Medical University, Wakayama, Japan.
Yuko IshidaDepartment of Forensic Medicine, Wakayama Medical University, Wakayama, Japan.
Akihiko KimuraDepartment of Forensic Medicine, Wakayama Medical University, Wakayama, Japan.
Yumi KuninakaDepartment of Forensic Medicine, Wakayama Medical University, Wakayama, Japan.
Akira TaruyaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Mitsunori OzakiDepartment of Neurological Surgery, Wakayama Medical University, Wakayama, Japan.
Atushi TanakaDepartment of Cardiovascular Medicine, Wakayama Medical University, Wakayama, Japan.
Naofumi MukaidaDivision of Molecular Bioregulation, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Toshikazu KondoDepartment of Forensic Medicine, Wakayama Medical University, Wakayama, Japan.
Wakayama Medical University · JPKanazawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After the ligation of the inferior vena cava (IVC) of wild-type (WT) mice, venous thrombi formed and grew progressively until 5 days and resolved thereafter. Concomitantly, intrathrombotic gene expression of

Indexed as

AnimalsGene Expression RegulationInterleukin-6MacrophagesMatrix Metalloproteinase 2Matrix Metalloproteinase 9MiceMice, Inbred BALB CMice, KnockoutPeptide HydrolasesThrombosisUrokinase-Type Plasminogen ActivatorVenous ThrombosisInterleukin-6interleukin-6, mouseMatrix Metalloproteinase 2Matrix Metalloproteinase 9Mmp2 protein, mouseMmp9 protein, mousePeptide HydrolasesUrokinase-Type Plasminogen ActivatorIL-6macrophagesmatrix metalloproteinasesproteolytic enzymesthrombosis

Identifiers

PMID32117207
PMCPMC7019028
OpenAlexW3005226122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.