Evidence map›Paper›PMID 32117143›Full record

ArticleFrontiers in microbiology2020

Distinct Types of Gut Microbiota Dysbiosis in Hospitalized Gastroenterological Patients Are Disease Non-related and Characterized With the Predominance of Either

Aleksander Mahnic, Martin Breskvar, Saso Dzeroski, Pavel Skok, Spela Pintar, Maja Rupnik

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 33 citations in OpenAlex.

  1. Evaluation of false positive enteric viruses results from the BIOFIRE® FILMARRAY® gastrointestinal PCR panel.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2026
    Article
  2. Impact of probiotic, prebiotic, and synbiotic supplementation on the gut microbiome in older adults with sarcopenia, obesity, and sarcopenic obesity.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  3. Adjunctive use ofTranslational gastroenterology and hepatology · 2026
    Article
  4. Article
  5. Article
  6. TIGITBMC cancer · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Gut Microbiota Composition Associated withPathogens (Basel, Switzerland) · 2022
    Review
  11. Review
  12. Gut community alterations associated withFrontiers in microbiology · 2022
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Interplay between gut microbiota and antimicrobial peptides.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2020
    Review
  18. Digital microbiology.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Review
  19. Dynamics of the Honeybee (Microorganisms · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Aleksander MahnicNational Laboratory for Health, Environment and Food, Department for Microbiological Research, Maribor, Slovenia.
Martin BreskvarDepartment of Knowledge Technologies, Jozef Stefan Institute, Ljubljana, Slovenia.
Saso DzeroskiDepartment of Knowledge Technologies, Jozef Stefan Institute, Ljubljana, Slovenia.
Pavel SkokFaculty of Medicine, University of Maribor, Maribor, Slovenia.
Spela PintarDepartment of Gastroenterology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Maja RupnikNational Laboratory for Health, Environment and Food, Department for Microbiological Research, Maribor, Slovenia.
Jožef Stefan Institute · SIJožef Stefan International Postgraduate School · SILjubljana University Medical Centre · SINational Laboratory of Health, Environment and Food · SIUniversity Clinical Centre Maribor · SIUniversity of Maribor · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Typical disease-associated microbiota changes are widely studied as potential diagnostic or therapeutic targets. Our aim was to analyze a hospitalized cohort including various gastroenterological pathologies in order to fine-map the gut microbiota dysbiosis. Bacterial (V3 V4) and fungal (ITS2) communities were determined in 121 hospitalized gastrointestinal patients from a single ward and compared to 162 healthy controls. Random Forest models implemented in this study indicated that the gut community structure is in most cases not sufficient to differentiate the subjects based on their underlying disease. Instead, hospitalized patients in our study formed three distinct disease non-related clusters (C1, C2, and C3), partially explained by antibiotic use. Majority of the subjects (cluster C1) closely resembled healthy controls, showing only mild signs of community disruption; most significantly decreased in this cluster were

Indexed as

dysbiosisEnterobacteriaceaeEnterococcusfungiguthospitalizationmachine learning

Identifiers

PMID32117143
PMCPMC7026674
OpenAlexW3006236807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.