Evidence map›Paper›PMID 32117106›Full record

ArticleFrontiers in microbiology2020

The Uptake, Trafficking, and Biodistribution of

Emily J Jones, Catherine Booth, Sonia Fonseca, Aimee Parker, Kathryn Cross, Ariadna Miquel-Clopés, Isabelle Hautefort, Ulrike Mayer, Tom Wileman, Régis Stentz and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 1 pooled it
14.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 1 synthesis or guideline pooled it, 192 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
  7. Article
  8. Infection and immunity · 2026
    Article
  9. Article
  10. Effect of gut bacterial extracellular vesicles on angiogenic potential and vascular integrity: positive and negative aspects.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
  11. Article
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79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Emily J JonesGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Catherine BoothCore Science Resources, Quadram Institute Bioscience, Norwich, United Kingdom.
Sonia FonsecaGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Aimee ParkerGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Kathryn CrossCore Science Resources, Quadram Institute Bioscience, Norwich, United Kingdom.
Ariadna Miquel-ClopésGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Isabelle HautefortEarlham Institute, Norwich, United Kingdom.
Ulrike MayerBiomedical Research Centre, University of East Anglia, Norwich, United Kingdom.
Tom WilemanGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Régis StentzGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Simon R CardingGut Microbes and Health Research Programme, Quadram Institute Bioscience, Norwich, United Kingdom.
Quadram Institute · GBUniversity of East Anglia · GBEarlham Institute · GB

Funding

Biotechnology and Biological Sciences Research Council BB/L004291/1Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10355
6 · The paper itself

Abstract

Gram-negative bacteria ubiquitously produce and release nano-size, non-replicative outer membrane vesicles (OMVs). In the gastrointestinal (GI-) tract, OMVs generated by members of the intestinal microbiota are believed to contribute to maintaining the intestinal microbial ecosystem and mediating bacteria-host interactions, including the delivery of bacterial effector molecules to host cells to modulate their physiology. Bacterial OMVs have also been found in the bloodstream although their origin and fate are unclear. Here we have investigated the interactions between OMVs produced by the major human gut commensal bacterium,

Indexed as

bacterial extracellular vesiclesBacteroides thetaiotaomicronbiodistributionGI-tractgut microbiotamicrovesiclesorganoid monolayerouter membrane vesicles

Identifiers

PMID32117106
PMCPMC7015872
OpenAlexW3004817752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.