Evidence map›Paper›PMID 32117052›Full record

SynthesisFrontiers in endocrinology2020

Added Value of Impact Microindentation in the Evaluation of Bone Fragility: A Systematic Review of the Literature.

Manuela Schoeb, Neveen A T Hamdy, Frank Malgo, Elizabeth M Winter, Natasha M Appelman-Dijkstra

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Bone Fragility: Time to Address the Matrix.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Obesity and Skeletal Fragility.The Journal of clinical endocrinology and metabolism · 2024
    Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Bone material strength index as measured by in vivo impact microindentation is normal in subjects with high-energy trauma fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Article
  16. Fracture risk assessment in diabetes mellitus.Frontiers in endocrinology · 2022
    Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Manuela SchoebDepartment of Medicine, Division of Endocrinology and Center for Bone Quality, Leiden University Medical Center, Leiden, Netherlands.
Neveen A T HamdyDepartment of Medicine, Division of Endocrinology and Center for Bone Quality, Leiden University Medical Center, Leiden, Netherlands.
Frank MalgoDepartment of Medicine, Division of Endocrinology and Center for Bone Quality, Leiden University Medical Center, Leiden, Netherlands.
Elizabeth M WinterDepartment of Medicine, Division of Endocrinology and Center for Bone Quality, Leiden University Medical Center, Leiden, Netherlands.
Natasha M Appelman-DijkstraDepartment of Medicine, Division of Endocrinology and Center for Bone Quality, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current gold standard for the diagnosis of osteoporosis and the prediction of fracture risk is the measurement of bone mineral density (BMD) using dual energy x-ray absorptiometry (DXA). A low BMD is clearly associated with increased fracture risk, but BMD is not the only determinant of bone strength, particularly in secondary osteoporosis and metabolic bone disorders in which components other than BMD are affected and DXA often underestimates true fracture risk. Material properties of bone which significantly contribute to bone strength have become evaluable

Indexed as

Equipment and SuppliesMicrotechnologySpecimen HandlingAbsorptiometry, PhotonBiopsy, NeedleBone and BonesBone DensityBone Diseases, MetabolicFractures, BoneHumansOsteoporosisOsteoporotic FracturesPredictive Value of TestsRisk Factorsbone material strength index (BMSi)bone mineral densitybone qualitydual energy x-ray absorptiometry (DXA)fracture riskosteoporosis primary and secondaryosteoproberare bone diseases

Identifiers

PMID32117052
PMCPMC7020781
OpenAlexW3004621467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.